The Effect of Anodal tDCS on Motor Learning in Multiple Sclerosis

June 1, 2013 updated by: Koen Cuypers, Hasselt University
The current study investigates the effects of tDCS in patients with multiple sclerosis (MS). The investigators hypothesize that anodal tDCS will increase motor performance in patients with MS.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

31

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 70 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • at least 18 years old
  • male and female

Exclusion Criteria:

  • relapse in the last 3 months
  • when not suitable for tDCS (screening)
  • if TMS measures can not be completed

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Sham Comparator: Sham tDCS
Device: Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)
The anode will be fixed over the primary motor cortex. The cathode will be fixed over the contralateral supraorbital region.
Other Names:
  • Neuroconn DC-stimulator
Active Comparator: Anodal tDCS
Device: Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)
The anode will be fixed over the primary motor cortex. The cathode will be fixed over the contralateral supraorbital region.
Other Names:
  • Neuroconn DC-stimulator

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Motor performance on a unimanual sequence learning task
Time Frame: Baseline, during training and POST (30 min after baseline) intervention
Patients were instructed to perform a unimanual sequence-learning task consisting of sequential finger presses. The following parameters were measured: Correct sequences/mean inter tap interval (ITI), percentage correct key presses/mean ITI, percentage correct sequences, percentage correct key presses, mean ITI, and mean correct sequences in the performance interval.
Baseline, during training and POST (30 min after baseline) intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hasselt University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

June 1, 2012

Primary Completion (Actual)

October 1, 2012

Study Completion (Actual)

October 1, 2012

Study Registration Dates

First Submitted

November 26, 2012

First Submitted That Met QC Criteria

November 30, 2012

First Posted (Estimate)

December 4, 2012

Study Record Updates

Last Update Posted (Estimate)

June 4, 2013

Last Update Submitted That Met QC Criteria

June 1, 2013

Last Verified

June 1, 2013

More Information

Terms related to this study

Other Study ID Numbers

  • MECU2012-003

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Clinical Trials on Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)

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