Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types

Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types

Sponsors

Lead Sponsor: Seoul National University Bundang Hospital

Source Seoul National University Bundang Hospital
Brief Summary

Repetitive transcranial magnetic stimulation induced virtual lesions for aphasia.

Detailed Description

To evaluate the effect of navigated repetitive transcranial magnetic stimulation in subjects with aphasia after stroke.

Overall Status Completed
Start Date December 2012
Completion Date May 2013
Primary Completion Date May 2013
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
The Change of Reaction Time Between Before and After Stimulation in Each Session (MTG, STG, Sham) change between before and after the TMS stimulation for each sessions (at session 1, session 2, session 3)
Enrollment 12
Condition
Intervention

Intervention Type: Device

Intervention Name: Repetitive magnetic stimulation to superior temporal gyrus

Description: Repetitive magnetic stimulation to superior temporal gyrus

Arm Group Label: Superior temporal gyrus

Other Name: MagPro X100 magnetic stimulator

Intervention Type: Device

Intervention Name: Repetitive magnetic stimulation to middle temporal gyrus

Description: Repetitive magnetic stimulation to middle temporal gyrus

Arm Group Label: Middle temporal gyrus

Other Name: MagPro X100 magnetic stimulator

Intervention Type: Device

Intervention Name: Repetitive magnetic stimulation (Sham)

Description: Repetitive magnetic stimulation (Sham)

Arm Group Label: Control group

Other Name: MagPro X100 magnetic stimulator

Eligibility

Criteria:

Inclusion Criteria:

- fluent in Korean

- older than 18 years old

Exclusion Criteria:

- younger than 18 years old

- psychotic or psychiatric problems

- pregnant

- contraindications to MRI/fMRI

- uncooperative

- metalic implants, pacemaker or cochlear implants

- cannot perform outcome measure-related task

- known seizure history

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: Accepts Healthy Volunteers

Overall Official
Last Name Role Affiliation
Nam-Jong Paik, MD, PhD Principal Investigator Seoul National University Bundang Hospital
Location
Facility: Seoul National University Bundang Hospital
Location Countries

Korea, Republic of

Verification Date

June 2017

Responsible Party

Type: Principal Investigator

Investigator Affiliation: Seoul National University Bundang Hospital

Investigator Full Name: Nam-Jong Paik

Investigator Title: Professor

Has Expanded Access No
Condition Browse
Number Of Arms 3
Arm Group

Label: Middle temporal gyrus

Type: Experimental

Description: Repetitive magnetic stimulation to middle temporal gyrus

Label: Control group

Type: Sham Comparator

Description: Repetitive magnetic stimulation (Sham)

Label: Superior temporal gyrus

Type: Experimental

Description: Repetitive magnetic stimulation to superior temporal gyrus

Study Design Info

Allocation: Randomized

Intervention Model: Crossover Assignment

Primary Purpose: Treatment

Masking: Single (Participant)

Source: ClinicalTrials.gov