Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types
June 26, 2017 updated by: Nam-Jong Paik, Seoul National University Bundang Hospital
Repetitive transcranial magnetic stimulation induced virtual lesions for aphasia.
Study Overview
Status
Completed
Conditions
Detailed Description
To evaluate the effect of navigated repetitive transcranial magnetic stimulation in subjects with aphasia after stroke.
Study Type
Interventional
Enrollment (Actual)
12
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Bundang-gu
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Seongnam-si, Bundang-gu, Korea, Republic of, 463-707
- Seoul National University Bundang Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (ADULT, OLDER_ADULT)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- fluent in Korean
- older than 18 years old
Exclusion Criteria:
- younger than 18 years old
- psychotic or psychiatric problems
- pregnant
- contraindications to MRI/fMRI
- uncooperative
- metalic implants, pacemaker or cochlear implants
- cannot perform outcome measure-related task
- known seizure history
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: TREATMENT
- Allocation: RANDOMIZED
- Interventional Model: CROSSOVER
- Masking: SINGLE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
EXPERIMENTAL: Middle temporal gyrus
Repetitive magnetic stimulation to middle temporal gyrus
|
Repetitive magnetic stimulation to middle temporal gyrus
Other Names:
|
|
SHAM_COMPARATOR: Control group
Repetitive magnetic stimulation (Sham)
|
Repetitive magnetic stimulation (Sham)
Other Names:
|
|
EXPERIMENTAL: Superior temporal gyrus
Repetitive magnetic stimulation to superior temporal gyrus
|
Repetitive magnetic stimulation to superior temporal gyrus
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
The Change of Reaction Time Between Before and After Stimulation in Each Session (MTG, STG, Sham)
Time Frame: change between before and after the TMS stimulation for each sessions (at session 1, session 2, session 3)
|
Reaction time for lexical and repetition test were measured before and after the TMS stimulation at each sessions (at session 1, session 2, session 3 over MTG/STG/Sham; MTG: middle temporal gyrus, STG: superior temporal gyrus). Response times were measured via the response pad, and spoken responses were recorded via a SV-1 Voice Key apparatus. The "reaction time post TMS - reaction time pre TMS" were used for analysis.* Arm/Group Title Arm/Group Description Maximum length (999) Repetitive magnetic stimulation (rTMS) were applied over STG |
change between before and after the TMS stimulation for each sessions (at session 1, session 2, session 3)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
December 1, 2012
Primary Completion (ACTUAL)
May 1, 2013
Study Completion (ACTUAL)
May 1, 2013
Study Registration Dates
First Submitted
March 11, 2013
First Submitted That Met QC Criteria
June 10, 2013
First Posted (ESTIMATE)
June 13, 2013
Study Record Updates
Last Update Posted (ACTUAL)
July 31, 2017
Last Update Submitted That Met QC Criteria
June 26, 2017
Last Verified
June 1, 2017
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- E-1206-158-003
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.