- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01950793
A Comparison Between Sonoguided Injection Corticosteroid and Hyaluronic Acid Injection in Treatment of Trigger Finger
Steroid Versus Hyaluronic Acid Ultrasound-guided Injection for Trigger Finger: A Comparative Study of Outcomes
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
-
Taipei, Taiwan
- Taipei Veterans General Hospital
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- patients with trigger digits and patients
- without previous treatment of the trigger digit
Exclusion Criteria:
- patients with prior treatment of the trigger digit (eg, splinting, injection, or therapy),
- patients less than
- 20 years old,
- patients with allergy or contraindication to hyaluronic acid,
- patients with trigger digits due to rheumatoid arthritis,
- and patients with infection at the site of injection.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: steroid
used ultrasound-guided inject 1c.c triamcinolone acetonide 10mg/mL (Shincort®, YSP, Taiwan)into the sheath of the flexor tendons, penetrated to the A1 pulley. One injection only |
used ultrasound-guided inject 1c.c triamcinolone acetonide 10mg/mL (Shincort®, YSP, Taiwan)into the sheath of the flexor tendons, penetrated to the A1 pulley. One injection only Steroid
Other Names:
|
Experimental: Hyaluronic acid
used ultrasound-guided inject 1c.c Hyaluronic acid (Artz®, Seikagaku, Japan)into the sheath of the flexor tendons, penetrated to the A1 pulley. One injection only |
used ultrasound-guided inject 1c.c Hyaluronic acid (Artz®, Seikagaku, Japan)into the sheath of the flexor tendons, penetrated to the A1 pulley. One injection only
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Quinnell classification
Time Frame: Pre-injection; 3-weeks and 3-months post-injections
|
he Quinnell system grades trigger fingers as: 0 - normal movement
|
Pre-injection; 3-weeks and 3-months post-injections
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
hand functional evaluation
Time Frame: Pre-injection; 3-weeks and 3-months post-injections
|
using the Michigan Hand Outcome Questionnaire (MHQ)
|
Pre-injection; 3-weeks and 3-months post-injections
|
visual analog scale
Time Frame: Pre-injection; 3-weeks and 3-months post-injections
|
Pre-injection; 3-weeks and 3-months post-injections
|
|
total active motion (TAM)
Time Frame: Pre-injection; 3-weeks and 3-months post-injections
|
Defi ned as the total ROM achieved when all three joints-metacarpophalangeal (MCP), proximal interphalangeal (PIP) and distal interphalangeal (DIP) of a digit are actively fl exed or extended simultaneously, minus any extension defi cit at any of the three joints
|
Pre-injection; 3-weeks and 3-months post-injections
|
grip strength
Time Frame: Pre-injection; 3-weeks and 3-months post-injections
|
dynamometer strength test (JAMAR grip)
|
Pre-injection; 3-weeks and 3-months post-injections
|
Collaborators and Investigators
Investigators
- Study Chair: Chung-Lan Kao, MD, PhD, Taipei Veterans General Hospital, Taiwan
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Musculoskeletal Diseases
- Muscular Diseases
- Tendinopathy
- Tendon Entrapment
- Trigger Finger Disorder
- Physiological Effects of Drugs
- Molecular Mechanisms of Pharmacological Action
- Enzyme Inhibitors
- Anti-Inflammatory Agents
- Immunosuppressive Agents
- Immunologic Factors
- Glucocorticoids
- Hormones
- Hormones, Hormone Substitutes, and Hormone Antagonists
- Protective Agents
- Adjuvants, Immunologic
- Viscosupplements
- Triamcinolone
- Triamcinolone Acetonide
- Triamcinolone hexacetonide
- Triamcinolone diacetate
- Hyaluronic Acid
Other Study ID Numbers
- 2012-11-001A
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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