Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation

Population Based Intervention Trial of Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation

The hypothesis of this study is Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NAD-CPR) would improve survival of out-of-hospital cardiac arrest (OHCA).

Study Overview

• Status: Completed
• Conditions: Out of Hospital Cardiac Arrest
• Intervention / Treatment: Other: NAD-CPR

Detailed Description

Out-of-hospital cardiac arrest (OHCA) is a major health problem, occurring in about 1 in 1,500 adults in the developed countries each year. Although layperson CPR and defibrillation are crucial components of chain of survival, layperson CPR rate and it's quality is low and public-access defibrillation (PAD) program is not cost-effective.If trained bystanders can know the information of occurrence of OHCA and nearest place for automated external defibrillator (AED) at the same time by dispatch center, these neighborhoods could run and give high quality CPR and early defibrillation. If this protocol ,Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation(NAD-CPR), is introduced to community, it may improve survival of OHCA.

• Study Type: Interventional
• Enrollment (Actual): 3194
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Korea, Republic of
  • Seoul, Korea, Republic of
    • Seoul Metropolitan City

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 15 years and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• all OHCA with presumed cardiac etiology more than 15 years old
• assessed by emergency medical service (EMS) providers dispatched by dispatch center
• dispatcher detected OHCA patients

Exclusion Criteria:

• OHCA with non-cardiac etiology
• prolonged cardiac arrest with a suspected duration more than 30 minutes
• cases with rigor mortis or rivor mortis, decapitated or decomposed body
• Non detected cases by dispatcher

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Non-Randomized
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: NAD-CPR; When dispatcher detects a patient with OHCA, the dispatcher activates trained neighborhoods by informing events nearby using short message service via cellular phone. The neighborhood within geographically accessible area who could perform effective CPR and defibrillation would be alerted with event of OHCA and the nearest AED.	Other: NAD-CPR; When Dispatcher detects OHCA, short message service (SMS)about the OHCA event and information about the location of nearest AED is sent to trained laypersons within geographically accessible area.
No Intervention: Conventional dispatcher assisted CPR; When dispatcher detects OHCA, they instruct the caller with CPR instructions. This is conventional dispatcher assisted CPR performed in Seoul.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of Participants Surviving at Hospital Discharge	we compared the survival to discharge rate between before intervention period and intervention period. Survival to discharge checked at the discharge point of hospital.	discharge time from first admission from emergency department within 2 month

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of Participants With Pre-Hospital Return of Spontaneous Circulation (ROSC)	we compared the Pre-hospital return of spontaneous circulation (ROSC) rate between before intervention period and intervention period.	hospital arriving time from ambulance within 2 hours
Number of Participants With Good Neurological Recovery	Cerebral performance category 1 or 2 is defined as good neurological recovery. we compared the good neurological recovery rate between before intervention period and intervention period.	discharge time from first admission from emergency department within 2 month

Collaborators and Investigators

• Sponsor: Seoul National University Hospital
• Collaborators: Korean Center for Disease Control and Prevention; Seoul Metropolitan Government Health and Welfare Office; Seoul Metropolitan Fire and Disaster Headquater; Korea Association for Safety Community
• Investigators: Principal Investigator: Sang Do Shin, MD, PhD, Seoul National University Hospital

Publications and helpful links

General Publications

• Lee SY, Shin SD, Lee YJ, Song KJ, Hong KJ, Ro YS, Lee EJ, Kong SY. Text message alert system and resuscitation outcomes after out-of-hospital cardiac arrest: A before-and-after population-based study. Resuscitation. 2019 May;138:198-207. doi: 10.1016/j.resuscitation.2019.01.045. Epub 2019 Mar 19.

Study record dates

Study Major Dates

• Study Start (Actual): March 1, 2015
• Primary Completion (Actual): December 1, 2017
• Study Completion (Actual): December 1, 2017

Study Registration Dates

• First Submitted: December 9, 2013
• First Submitted That Met QC Criteria: December 9, 2013
• First Posted (Estimate): December 12, 2013

Study Record Updates

• Last Update Posted (Actual): March 30, 2020
• Last Update Submitted That Met QC Criteria: March 16, 2020
• Last Verified: March 1, 2020

More Information

Terms related to this study

• Keywords: Cardiopulmonary Resuscitation; emergency medicine; Out of Hospital Cardiac Arrest; dispatch
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Arrest; Out-of-Hospital Cardiac Arrest
• Other Study ID Numbers: SNUEMS201309