Explore the Association Between the Emotion Recognition and the Attention Processing Under the Emotional Stimuli in ADHD

Lots of studies suggest that children with ADHD have deficits in facial emotion recognition, especially for the negative emotion. But there were arguments for this deficit is a secondary problem due to the general attention impairment in ADHD, or a specific social cognitive processing to ADHD. The objectives of this study are to investigate that association between the deficits in facial emotion recognition and the emotional attention processing in ADHD. In this study, the investigators use the emotion attentional bias and emotional go / no go paradigm to answer this question.

Study Overview

• Status: Unknown
• Conditions: Attention Deficit/Hyperactivity Disorder

Detailed Description

The sample will consist of 100 children and adolescent with ADHD and 100 typical controls, ages 8-16. The ADHD group inclusion criteria are patients who have clinically diagnosis of DSM-IV ADHD confirmed by the K-SADS-E, and have IQ > 80; and whose parents consent to this study.

The measurements will be included:

1. Diagnostic assessment tools:

   • Chinese version of Kiddie-Schedule for Affective Disorders and Schizophrenia-Epidemiology version.
   • Conners' Parent/Teacher Rating Scale- Revised: Short Form, CPRS-R:S/CTRS-R:S.
   • Swanson, Nolan, and Pelham, Version Ⅳ（SNAP-Ⅳ）Rating Scale - Parent/ Teacher Form.

2. Emotion assessment tools:

   • Facial emotion recognition task.
   • Emotional attentional bias task.
   • Emotional Go/ No Go task.

3. Cognitive assessment tool:

   • Wechsler Intelligence Scale for Children-Fourth Edition Chinese Version.

This study could offer the suggestion for the further intervention of social function in ADHD.

• Study Type: Observational
• Enrollment (Anticipated): 200

Contacts and Locations

Study Locations

• Taiwan
  • Taipei, Taiwan
    • Recruiting
    • National Taiwan Univeristy Hospital
    • Contact: Susan Shur-Fen Gau, MD, PhD; Phone Number: 66802 886-2-23123456; Email: gaushufe@ntu.edu.tw

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 4 years to 12 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

We will recruit 100 children and adolescent with ADHD and 100 typical controls.

Description

Inclusion Criteria:

1. Control group

   • The subjects without ADHD.
   • Ages range from 8 to 16
   • Full scale IQ ≥ 80
   • The subjects who and whose parents consent to this study.

2. ADHD group

   • Patients who have clinically diagnosis of DSM-IV ADHD confirmed by the K-SADS-E.
   • Ages range from 8 to 16
   • Full scale IQ ≥ 80
   • Patients who and whose parents consent to this study.

Exclusion Criteria:

• Mental Retardation
• Schizophrenia, Schizoaffective Disorder
• Mood Disorders
• Organic Psychosis
• Learning Disorder
• Pervasive Developmental Disorder
• The subjects of control group if have a history of the following condition as defined by DSM-IV: ADHD in addition to the above exclusion criteria will be excluded.

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Control

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The error rate in facial emotion judgements on computerized task	Investigator used the e-prime program to assess the error rate in facial emotion judgements. Participants need to judge the emotion of the face stimuli presented on the laptop.	up to 2 years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The reaction time of attentional bias for pairs of face stimuli(happy/neutral or angry/neutral faces) on dot-prob task	Investigator presented pairs of face stimuli with emotional and neutral expressions and probed the allocation of attention to these stimuli for presentation times of 150 and 500 ms to assess the reaction time of attentional bias. Participants need to press the dot after the prob.	up to 2 years

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
The attentional inhibition control(omission errors and commission errors) in emotional go/no go task	Investigator used go/ no go task to assess participants' omission errors and commission errors, participants just need to press the keyboard and the number of errors were recorded.	up to 2 years

Collaborators and Investigators

• Sponsor: National Taiwan University Hospital
• Collaborators: National Science Council, Taiwan
• Investigators: Principal Investigator: Susan Shur-Fen Gau, MD, PhD, National Taiwan University Hospital

Study record dates

Study Major Dates

• Study Start: July 1, 2013
• Primary Completion (Anticipated): January 1, 2016
• Study Completion (Anticipated): January 1, 2016

Study Registration Dates

• First Submitted: December 4, 2013
• First Submitted That Met QC Criteria: December 16, 2013
• First Posted (Estimate): December 20, 2013

Study Record Updates

• Last Update Posted (Estimate): December 20, 2013
• Last Update Submitted That Met QC Criteria: December 16, 2013
• Last Verified: December 1, 2013

More Information

Terms related to this study

• Keywords: attention; emotion recognition; ADHD,
• Additional Relevant MeSH Terms: Mental Disorders; Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Attention Deficit Disorder with Hyperactivity
• Other Study ID Numbers: 201211008RIB