Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease

April 22, 2015 updated by: Marcely Kellyane Florenço Barros, Universidade Federal de Pernambuco
This study aimed to evaluate the acute effect of PLB technique on diaphragmatic mobility, the kinematics of the thoracoabdominal complex analysis of lung volumes and exercise tolerance in patients with Chronic Obstructive Pulmonary Disease (COPD). This is a study randomized cross-over clinical trial and blind, in subjects with Chronic Obstructive Pulmonary Disease (COPD) according to criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (FEV1 / FVC <0.7 and FEV1 <80% predicted) selected at the Clinical Hospital of the Federal University of Pernambuco (UFPE) and Otavio de Freitas General Hospital (HGOF). The investigators recruited 13 patients COPD (according to previous sample calculation) aged between 40 and 80 years, of both sexes. The first day was held evaluation of lung function, respiratory muscle strength, body composition, dyspnea index and functional capacity. On the second day was held evaluation of thoracoabdominal complex kinematics by plethysmography Optoelectronics (OEP) with Quiet Breathing (QB) or pursed-lips breathing (PLB). Lung volumes with 2 minutes with QB and 6 minutes PLB or only 6 minutes by QB as randomization were observed. Before and after performing the requested breathing pattern diaphragmatic mobility was observed by Ultrasonography (US) and requested the patient an Inspiratory Capacity maneuver (IC). The evaluator who performed the ultrasound was blinded as to the beginning of the breathing pattern of order performed by the patient.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

14

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Brazil
    • Pernambuco
      • Recife, Pernambuco, Brazil
        • Clinical Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

40 years to 80 years (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • COPD diagnosis with stage II-IV (GOLD),
  • Stable clinical condition (no exacerbation or hospital admission in the last four weeks preceding the study)
  • Absence of other disease that may potentially contribute to dyspnea (heart disease, congestive heart failure, neuromuscular diseases, severe postural changes)

Exclusion Criteria:

  • BMI> 30 kg / m2
  • Musculoskeletal limitations
  • Use of oxygen therapy
  • Extreme discomfort during the procedure application

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: SUPPORTIVE_CARE
  • Allocation: RANDOMIZED
  • Interventional Model: CROSSOVER
  • Masking: DOUBLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Quiet Breathing or Pursed Lips Breathing
Free or natural breathing for six minutes.
Other: Pursed Lips Breathing
Pursed Lips Breathing for six minutes.
Other: Quiet Breathing

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Chest wall (Analysis of lung volumes)
Time Frame: One day during eight minutes
(L) by plethysmography optoelectronics.
One day during eight minutes
Mobility diaphragmatic (mobility diaphragmatic (mm) by Ultrassonography)
Time Frame: One day, before and after eight minutes of pursed lips breathing
Analysis of mobility diaphragmatic (mm) by Ultrassonography.
One day, before and after eight minutes of pursed lips breathing
Exercise tolerance (Glittre AVD-Test)
Time Frame: One day, for six minutes approximately. The test will be repeated after 20 minutes of rest.
Analysis by Glittre AVD-Test (capacity functional test) observing the test execution time (s).
One day, for six minutes approximately. The test will be repeated after 20 minutes of rest.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Dyspnea (Borg and MRC Scale)
Time Frame: One day, before and after implementation of Glittre-ADL Test
Assessed by Borg and MRC Scale (Medical Research Council).
One day, before and after implementation of Glittre-ADL Test

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universidade Federal de Pernambuco

Investigators

  • Study Director: Armele D Andrade, Dra, Universidade Federal de Pernambuco

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2014

Primary Completion (ACTUAL)

January 1, 2015

Study Completion (ACTUAL)

March 1, 2015

Study Registration Dates

First Submitted

March 5, 2015

First Submitted That Met QC Criteria

April 22, 2015

First Posted (ESTIMATE)

April 23, 2015

Study Record Updates

Last Update Posted (ESTIMATE)

April 23, 2015

Last Update Submitted That Met QC Criteria

April 22, 2015

Last Verified

April 1, 2015

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 19309213.3.0000.5208

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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