Effects of Birth Weight on Anterior Eye Segment Measurements in Full-Term Children by Galilei Dual-Scheimpflug Analyzer

This study evaluates the effects of birth weight (BW) on ocular anterior segment parameters in preschool children using the Galilei Dual-Sheimpflug Analyzer (GD-SA). Children were measured by GD-SA and relationships between all anterior segment parameters obtained by this device and birth weight were analyzed.

Study Overview

• Status: Completed
• Conditions: Birth Weight
• Intervention / Treatment: Device: Galilei Dual-Scheimpflug Analyzer

Detailed Description

Preschoolers, who were born heavier, had thicker cornea and lens, longer axial length, and flatter corneal curve. The thicknesses and axial curves of central cornea within 7mm may be particularly associated with BW.

• Study Type: Observational
• Enrollment (Actual): 78

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 11 months to 3 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Healthy children aged between 3-6- preschoolers- born at term and have birth weight heavier than 2500g

Description

Inclusion Criteria:

• ages 3- 6 years;
• birth weight >2,500 g;
• gestational age (i.e., the period of time between the first day of the mother's last menstrual period and birth) >37 weeks;
• visual acuity >0.8 (in decimals);
• no history of any systemic or ocular diseases;
• no history of previous ocular surgeries;
• no retinopathy of prematurity;
• no current medications; and
• no retinal or optic disc abnormalities on fundoscopy.

Exclusion Criteria:

• ages <3 >6 years;
• birth weight <2,500 g;
• gestational age (i.e., the period of time between the first day of the mother's last menstrual period and birth) <37 weeks;
• visual acuity <0.8 (in decimals);
• history of any systemic or ocular diseases;
• history of previous ocular surgeries;
• retinopathy of prematurity;
• current medications; and
• retinal or optic disc abnormalities on fundoscopy.

Study Plan

How is the study designed?

Design Details

• Time Perspectives: Cross-Sectional

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Birth Weight	Device: Galilei Dual-Scheimpflug Analyzer; Measuring of Anterior Segment by Galilei Dual-Scheimpflug Analyzer

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Measurements of anterior segment parameters in Full-Term Children by Galilei Dual-Scheimpflug Analyzer	Corneal parameters, anterior chamber parameters and lens thickness were measured by Galilei Dual-Scheimpflug Analyzer in healthy preschool children.	1 day

Collaborators and Investigators

• Sponsor: Neon Hospital
• Collaborators: Ondokuz Mayıs University

Study record dates

Study Major Dates

• Study Start: January 1, 2011
• Primary Completion (Actual): March 1, 2013
• Study Completion (Actual): March 1, 2013

Study Registration Dates

• First Submitted: June 3, 2015
• First Submitted That Met QC Criteria: June 4, 2015
• First Posted (Estimate): June 9, 2015

Study Record Updates

• Last Update Posted (Estimate): June 9, 2015
• Last Update Submitted That Met QC Criteria: June 4, 2015
• Last Verified: June 1, 2015

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Body Weight; Birth Weight
• Other Study ID Numbers: 2010-171