Breath-hold Cardiac Hybrid SPECT/CCTA

May 10, 2016 updated by: University of Zurich

Usefulness of Breath-hold Triggered SPECT-MPI in Cardiac Hybrid SPECT/CCTA Imaging

This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Switzerland
      • Zurich, Switzerland, 8091
        • Department of Nuclear Medicine, University Hospital Zurich

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Referral for cardiac hybrid SPECT/CCTA
  • Male and female subjects 18 years of age or older
  • Written informed consent by the participant after information about the project

Exclusion Criteria:

  • Contraindications for coronary CT angiography (including renal failure with a GFR <30ml/min/1.73m2, allergies to iodinated contrast agents)
  • Pregnancy or breast-feeding
  • Previous coronary revascularisation
  • Inability to follow the examination procedure (e.g. due to language barriers, severe mental disease etc

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: DIAGNOSTIC
  • Allocation: NA
  • Interventional Model: SINGLE_GROUP
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI
Device: Breathhold SPECT-MPI
Respiratory triggered SPECT myocardial perfusion imaging
Device: Standard freebreathing SPECT-MPI
Clinically indicated, standard non-respiratory triggered SPECT myocardial perfusion imaging
Device: Coronary CT angiography
Clinically indicated coronary CT angiography serving as standard of reference
Other Names:
  • CCTA

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Image quality as visually assessed on a Likert scale
Time Frame: 1 day
1 day
Number of image artefacts
Time Frame: 1 day
1 day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Zurich

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2015

Primary Completion (Actual)

May 1, 2016

Study Completion (Actual)

May 1, 2016

Study Registration Dates

First Submitted

May 13, 2015

First Submitted That Met QC Criteria

June 8, 2015

First Posted (Estimate)

June 11, 2015

Study Record Updates

Last Update Posted (Estimate)

May 11, 2016

Last Update Submitted That Met QC Criteria

May 10, 2016

Last Verified

May 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • USZ-2015-0098

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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