Study of Effects of Light on the Vigilance and Cognitive Performance Following a Night Without Sleep (LUMI)

Sleep disorders are a major public health issue, affecting 1 in 6 French. The medical impact at the individual level but also social and economic level (loss of productivity, morbidity, mortality) emphasize the need for one hand, to improve the investigators' understanding of these disorders in order to develop appropriate therapeutic tools and on the other hand, to increase the investigators' support abilities of patients with these disorders.

The investigators' team of unity sleep from Strasbourg University Hospitals, in collaboration with the UPR 3212 CNRS team, is working on the development and adjustment of new concepts and tools to compensate the investigators' sleep debt in order to apply them to patients with sleep disorders and persons who face with sleep restriction.

Study Overview

• Status: Completed
• Conditions: Healthy Volunteers
• Intervention / Treatment: Device: Energy-Light lamp; Device: Luminettes lamp; Other: control condition

• Study Type: Interventional
• Enrollment (Actual): 18
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • Strasbourg, France, 67091
    • Unité du Sommeil - Hôpitaux Universitaires de Strasbourg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Man or woman
• Age from 18 to 40 years
• With a Body Mass Index (BMI) between 17 and 30 kg m-2
• Healthy volunteer determined by clinical examination and psychological interview
• Agreeing to abstain from caffeine, nicotine, alcohol, psychotropic drugs, cannabis or other drugs, the week before the start of Stage 2 of the study until the end of the study
• Dated and signed informed consent
• Subjet affiliated to a social security scheme
• Subject has been informed about the results of the medical examination

Exclusion Criteria:

• Participation in other clinical trials in the month preceding the inclusion
• Shift work in the year before inclusion
• Cons-indications to the use of the medical device
• Ocular disease
• Unable to give informations to the subject (subject in an emergency situation, difficulties in understanding, ...)
• Subjet under judicial protection
• Subject under guardianship or curatorship
• pregnancy
• breastfeeding

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Experimental	Device: Energy-Light lamp; Exposure of the subject, at 5am, to the light source of Energy-Light lamp (Philips); Device: Luminettes lamp; Exposure of the subject, at 5am, to the light source of Luminettes lamp (Lucimed); Other: control condition; No exposure of the subject to any light sources (control condition)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Analysis of the perception of fatigue	Karolinska Sleepiness Scale 3 sessions :	Compare during the 3 sessions : energy-light lamp, luminettes lamp and control condition
Analysis of the circadian variation of melatonin and cortisol secretion	cortisol and melatonin dosage	Compare during the 3 sessions : energy-light lamp, luminettes lamp and control condition

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Cognitive performance	neurobehavioral tests	Compare during the 3 sessions : energy-light lamp, luminettes lamp and control condition

Collaborators and Investigators

• Sponsor: University Hospital, Strasbourg, France

Publications and helpful links

General Publications

• Comtet H, Geoffroy PA, Kobayashi Frisk M, Hubbard J, Robin-Choteau L, Calvel L, Hugueny L, Viola AU, Bourgin P. Light therapy with boxes or glasses to counteract effects of acute sleep deprivation. Sci Rep. 2019 Dec 2;9(1):18073. doi: 10.1038/s41598-019-54311-x.

Study record dates

Study Major Dates

• Study Start: May 1, 2015
• Primary Completion (Actual): June 1, 2015
• Study Completion (Actual): June 1, 2015

Study Registration Dates

• First Submitted: January 26, 2015
• First Submitted That Met QC Criteria: June 17, 2015
• First Posted (Estimated): June 23, 2015

Study Record Updates

• Last Update Posted (Estimated): December 22, 2025
• Last Update Submitted That Met QC Criteria: December 15, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: 6191