- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02557230
Malignant Genito-urinary Tumors in Children: South Egypt Cancer Institute Experience
Study Overview
Status
Conditions
Detailed Description
Background:
Tumors of the kidney, bladder, prostate, testis, and adrenal represent a large part of the adult urologic practice, but are relatively infrequent in children.
Genitourinary tumors contribute to pediatric solid tumors. Wilms tumor, rhabdomyosarcoma, and germ cell tumors are the most common malignant genitourinary tumors in children.
The natural history and management of these tumors in the pediatric age is different from that of the adults. As result of the successful work of several clinical trial groups in recent decades, there has been a significant improvement in their cure rates.
Patients & Methods:
From January 2001 till December 2015, retrieval & analysis of the medical records of pediatric patients with genitourinary tumors will be made at the pediatric oncology department, South Egypt Cancer Institute which represents the largest referral center in Upper Egypt. These data will be categorized according to demographic characteristics, clinico-pathologic features, treatment modalities received, and outcomes of treatments in these patients.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Locations
-
-
-
Assiut, Egypt, 71515
- Recruiting
- Assiut University
-
Contact:
- Ahmed M. Morsy, MD
- Phone Number: +2 01003314522
- Email: ahmedmohammed7829@yahoo.com
-
Principal Investigator:
- Ahmed M. Morsy, MD
-
Principal Investigator:
- Khalid M. Rezk, MD
-
Principal Investigator:
- Ameer M. Abuelgheet, MD
-
Principal Investigator:
- Badawy M. Ahmed, MD
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients whose age less than or equal to 18 years.
- Patients diagnosed with any of neoplasms affecting the genitourinary system.
Exclusion Criteria:
- Patients whose age more than 18 years.
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Overall survival (OS)
Time Frame: Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years
|
Time from the date of initiation of treatment until death from any cause
|
Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years
|
Event Free Survival (EFS)
Time Frame: Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years
|
Time from the date of initiation of treatment until disease progression, or death for any reason.
|
Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years
|
Collaborators and Investigators
Sponsor
Publications and helpful links
General Publications
- Denes FT, Duarte RJ, Cristofani LM, Lopes RI. Pediatric genitourinary oncology. Front Pediatr. 2013 Dec 16;1:48. doi: 10.3389/fped.2013.00048.
- Lambert S. Adult Survivors of Pediatric Genitourinary Tumors. In: Wood HM, Wood D, editors. Transition and Lifelong Care in Congenital Urology: Springer International Publishing; 2015. p. 209-16.
Study record dates
Study Major Dates
Study Start
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimated)
Study Record Updates
Last Update Posted (Estimated)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Ped GU Tumors
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Genitourinary Neoplasms
-
National Yang Ming UniversityNational Science Council, TaiwanCompletedGenitourinary Symptoms
-
M.D. Anderson Cancer CenterPfizerTerminated
-
Duke UniversityArgos TherapeuticsTerminatedMetastatic Renal Cell Carcinoma | Genitourinary Cancer (Bladder, Prostate or Testicular)United States
-
Żelazna Medical Centre, LLCLaboratory of Genetics and Human Genomics, University of GdańskCompleted
-
Duke UniversityWallace H. Coulter FoundationCompletedCancer of the Gastrointestinal, Genitourinary or Gynecologic SystemsUnited States
-
59th Medical WingCompletedGenitourinary SymptomsUnited States
-
University of AarhusNot yet recruitingGenitourinary Syndrome of MenopauseDenmark
-
University of California, IrvineRecruitingGenitourinary Syndrome of MenopauseUnited States
-
Michigan Institution of Women's Health PCCompletedGenitourinary Syndrome of MenopauseUnited States
-
Universitaire Ziekenhuizen KU LeuvenRecruitingGenitourinary Syndrome of MenopauseBelgium