Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults (TNNS)

January 4, 2016 updated by: Monell Chemical Senses Center
The goal of the study is to determine whether there are age-, diet- and genetically-related differences in the perception of sweeteners, both nutritive and non-nutritive.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This is an observational 3-day study of children between the ages of 7 and 14 and their mothers. A variety of psychophysical methods determined liking for each of the sweeteners and saliva samples were obtained for genotyping of taste receptor genes. Anthropometric and dietary intake measures were also collected.

Study Type

Observational

Enrollment (Actual)

82

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

7 years to 60 years (Child, Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Healthy children and adults living in the Philadelphia area

Description

Inclusion Criteria:

  • Healthy

Exclusion Criteria:

  • Allergies and taking medication that affected taste

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Age Group-Children
Children between ages of 7 and 14
Other: sweeteners
Participants tasted a variety of nutritive and nonnutritive sweeteners
Age Group-Adults
Healthy adults who are the parent of the children
Other: sweeteners
Participants tasted a variety of nutritive and nonnutritive sweeteners

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Liking for the taste of sweeteners measured via the 3-point facial hedonic scale.
Time Frame: Through study completion, an average of 6 months.
Through study completion, an average of 6 months.
Liking for the taste of sweeteners measured via the 5-point facial hedonic scale
Time Frame: Through study completion, an average of 6 months.
Through study completion, an average of 6 months.
Liking for the taste of sweeteners measured via the Monell forced-choice, paired-comparison tracking procedure.
Time Frame: Through study completion, an average of 6 months.
Through study completion, an average of 6 months.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Genotyping of taste receptor genes via saliva donation
Time Frame: Through study completion, an average of 6 months
Genotyping will be completed to measure associations between individual taste receptor genotypes and liking of sweeteners.
Through study completion, an average of 6 months
BMI calculated from body weight and height measures
Time Frame: Through study completion, an average of 6 months
BMI will be calculated to examine associations between this measure and liking for sweeteners.
Through study completion, an average of 6 months
One day dietary intake collected via the Automated Self-Administered 24-hour dietary recall (ASA24).
Time Frame: Through study completion, an average of 6 months
Dietary recall will be completed to examine associations between added sugar intake and liking for sweeteners.
Through study completion, an average of 6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Monell Chemical Senses Center

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2014

Primary Completion (Actual)

September 1, 2015

Study Completion (Actual)

September 1, 2015

Study Registration Dates

First Submitted

December 18, 2015

First Submitted That Met QC Criteria

January 4, 2016

First Posted (Estimate)

January 6, 2016

Study Record Updates

Last Update Posted (Estimate)

January 6, 2016

Last Update Submitted That Met QC Criteria

January 4, 2016

Last Verified

December 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • NIH DC011287

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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