Effect of Activity Modification and Exercises in Young Adolescents With Osgood Schlatter Disease.

The purpose of this study is to investigate the effect of activity modification, exercises and a gradual return to sport in adolescents (age 10-14) with Osgood Schlatter disease. The primary outcome is self-reported recovery on a 7-point Likert scale at 3 months. Secondary endpoints include 4 and 8 weeks and 6 and 12 months after inclusion into the project. The adolescents will be recruited from primary schools, general practitioners and through online advertising on Facebook.

Study Overview

• Status: Completed
• Conditions: Osgood Schlatter Disease
• Intervention / Treatment: Other: Activity modification, exercises and gradual return to sport

• Study Type: Interventional
• Enrollment (Actual): 51
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Denmark
  • Hvidovre, Denmark, 2650
    • Hvidovre-Amager Hospital
  • The North Denmark Region
    • Aalborg, The North Denmark Region, Denmark, 9000
      • Aalborg Universitetshospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 10 years to 14 years (CHILD)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• 10-14 years of age
• Pain at tuberositas patellae during two or more of the following activities: Sitting with a bent knee, squatting, running, jumping or stair ambulation
• Pain during palpation of tuberositas patellae
• Knee pain for 6 weeks or more

Exclusion Criteria:

• Other knee conditions that may manifest as anterior knee pain (Patellofemoral pain, iliotibial band syndrome, sinding-larson-johanson disease).
• Previous surgery
• Pain from the hip or back that interferes with activities of daily living.
• Habitual patella luxations
• Clinical suspicion of meniscal lesion

Study Plan

How is the study designed?

Design Details

• Primary Purpose: TREATMENT
• Allocation: NA
• Interventional Model: SINGLE_GROUP
• Masking: NONE

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
EXPERIMENTAL: Activity modification, exercises and gradual return to sport	Other: Activity modification, exercises and gradual return to sport

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Self-reported recovery on a 7-point Likert scale	3 months

Secondary Outcome Measures

Outcome Measure	Time Frame
Self-reported recovery on a 7-point Likert scale	4 and 8 weeks + 6 and 12 months after inclusion.
Self-report questionnaire "Knee Injury and Osteoarthritis Outcome Score"	4, 8 and 12 weeks + 6 and 12 months after inclusion.
Isometric hip and knee extension strength assessed using a strap-mounted dynamometer	4, 8 and 12 weeks after inclusion.
Pressure pain thresholds at tuberositas patella, center of patella and lateral elbow assessed by a hand held pressure algometer.	4, 8 and 12 weeks after inclusion.
Thigh circumference measured using tape measure.	4, 8 and 12 weeks after inclusion.
Vertical jump for height [calculated as the difference between reach height and maximal jump height. This will be measured using a ruler]	4, 8 and 12 weeks after inclusion.
Single leg jump for distance (defined as the maximal length the subject can jump on one leg. Measured using a ruler).	4, 8 and 12 weeks after inclusion.
Flexibility of the hamstrings and quadriceps [measured using goniometer].	4, 8 and 12 weeks after inclusion.

Collaborators and Investigators

• Sponsor: Aalborg University

Publications and helpful links

General Publications

• Rathleff MS, Winiarski L, Krommes K, Graven-Nielsen T, Holmich P, Olesen JL, Holden S, Thorborg K. Activity Modification and Knee Strengthening for Osgood-Schlatter Disease: A Prospective Cohort Study. Orthop J Sports Med. 2020 Apr 6;8(4):2325967120911106. doi: 10.1177/2325967120911106. eCollection 2020 Apr.

Study record dates

Study Major Dates

• Study Start (ACTUAL): June 1, 2016
• Primary Completion (ACTUAL): December 1, 2017
• Study Completion (ACTUAL): December 1, 2017

Study Registration Dates

• First Submitted: June 10, 2016
• First Submitted That Met QC Criteria: June 10, 2016
• First Posted (ESTIMATE): June 14, 2016

Study Record Updates

• Last Update Posted (ACTUAL): January 30, 2018
• Last Update Submitted That Met QC Criteria: January 27, 2018
• Last Verified: January 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Bone Diseases; Osteochondrosis
• Other Study ID Numbers: N- 20140100-1

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: Data will be made publicly available no later than six months after the final publication.