- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02963194
Oxytocin Effects on Self and Other Processing
November 9, 2016 updated by: University of Electronic Science and Technology of China
To determine whether the neuropeptide oxytocin (OXT) influences self-processing by investigating whether it increases the endowment effect in relation to both self and others.
Study Overview
Detailed Description
In a double-blind, between- subject placebo (PLC) controlled design, investigator aimed to measure the effect of intranasal OXT on the endowment effect.
All subjects completed a range of questionnaires measuring personality and affective traits and levels of anxiety before self-administration: Positive and Negative Affect Schedule (PANAS) , State-Trait Anxiety Inventory (STAI) , Beck Depression Inventory (BDI), self-esteem scale (SES).
Subjects were asked to decide whether to buy or sell their own or others' (their mothers'/ fathers'/ classmate'/ strangers') possessions at various prices.
Indifference point and brain activation were inluded into analysis as dependent variables.
Study Type
Interventional
Enrollment (Actual)
44
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Sichuan
-
Chengdu, Sichuan, China, 611731
- School of Life Science and Technology, University of Electronic Science and Technology
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 27 years (ADULT)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
Male
Description
Inclusion Criteria:
- healthy subjects without past or current psychiatric or neurological disorders
Exclusion Criteria:
- history of head injury;
- claustrophobia;
- medical or psychiatric illness.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: BASIC_SCIENCE
- Allocation: RANDOMIZED
- Interventional Model: PARALLEL
- Masking: DOUBLE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: Oxytocin
Oxytoxin nasal spray
|
|
PLACEBO_COMPARATOR: Placebo
Placebo nasal spray
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Compared the indifference point between buy and sell conditions during the price phase and the specific brain region activation between oxytocin and placebo groups
Time Frame: 1 hour
|
Indifference point is the gap between willingness to accept and willingness to pay ;focus on the specfic brain region relasted to self-processing, such as medial prefrontal cortex, precuneus, posterior cingulate cortex, ventral striatum.
|
1 hour
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
November 1, 2015
Primary Completion (ACTUAL)
March 1, 2016
Study Completion (ACTUAL)
June 1, 2016
Study Registration Dates
First Submitted
April 15, 2016
First Submitted That Met QC Criteria
November 9, 2016
First Posted (ESTIMATE)
November 15, 2016
Study Record Updates
Last Update Posted (ESTIMATE)
November 15, 2016
Last Update Submitted That Met QC Criteria
November 9, 2016
Last Verified
November 1, 2016
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- UESTC-neuSCAN-05
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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