Is There Any Differences in Motor and Cognitive Development Between Preterm and Early Preterm Infants?

Is There Any Differences in Motor And Cognitive Development Between Preterm (<37 Weeks) and Early Preterm (<32 Weeks) Infants? Two Years Follow Up Study

Infant born preterm have an increased risk of adverse long-term developmental outcomes.The risk associated with preterm birth increase as gestational age decreases, and vulnerability remains in extremely- very preterm (<32 weeks) and moderate- late preterm (>32 weeks). There are many studies in the literature showed that the prevalence of developmental delay increases with premature birth. However, there is no study in the literature investigates long term follow up motor and cognitive development in subgroups of preterm infants . Hence the aim of this study is to evaluate the differences in motor and cognitive development in moderate-late (>32 weeks) and extremely-very preterm infants.

Study Overview

• Status: Withdrawn
• Conditions: Premature Baby
• Intervention / Treatment: Behavioral: family based intervention

Detailed Description

A convenience of infants with premature birth recruiting from Gazi University, Faculty of Health Science, Department of Physiotherapy and Rehabilitation. Babies divide into two groups according to the gestational ages. Babies with gestational ages between 32-36 weeks and 6 days (including the given days) are categorized as moderate-late preterm, while those born before 32 weeks are grouped as extremely and very preterm. Each group contains 20 babies. First, sociodemographic information and histories of babies are obtaining. Ages and contact information of the parents are recording. Prenatal and natal risk factors of the mothers are querying. Gestational ages and height, weight, and head circumferences of babies at birth are recording. Number of pregnancies, live births and abortions, type of delivery, multiple pregnancies for mothers as well as consanguinity between parents are asking.The Alberta Infant Motor Scale is using to evaluate spontaneous motor movements of the baby. It evaluates the baby at prone, supine, sitting, and standing positions. Bayley Scales of Infant and Toddler Development scales screen for cognitive, language, and motor development in babies. All infants will be testing in 3-6-9-12-15-18-24 months of ages.

• Study Type: Observational

Contacts and Locations

Study Locations

• Turkey
  • Ankara, Turkey, 06500
    • Gazi University, Faculty of Health and Sciences, Department of Physiotherapy and Rehabilitation

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: No older than 2 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

preterm infants born with <37 weeks.

Description

Inclusion Criteria:

• adjusted age of 24 months or less, born with a gestational age of 36 weeks and 6 days or earlier, not having any systemic disease, and accepting to join the study

Exclusion Criteria:

• age greater than 24 months and born with a gestational age of 37 weeks or more
• having major risk factor

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
moderate-early preterm infants; infant who births in 32 weeks to 37 weeks with family based intervention	Behavioral: family based intervention; behavioural advises to family for normal motor development
extremely-very preterm infants; infant who births in 27 weeks to 32 weeks with family based intervention	Behavioral: family based intervention; behavioural advises to family for normal motor development

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Motor development assessed with the Alberta Infant Motor Scale	The Alberta Infant Motor Scale is going to use	Each 3 months from beginning to two years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Cognitive development assessed with the Bayley Scales of Infant and Toddler Development	Bayley Scales of Infant and Toddler Development	Each 3 months from beginning to two years

Collaborators and Investigators

• Sponsor: Gazi University

Study record dates

Study Major Dates

• Study Start (Actual): February 9, 2014
• Primary Completion (Actual): February 2, 2017
• Study Completion (Actual): September 27, 2018

Study Registration Dates

• First Submitted: January 27, 2017
• First Submitted That Met QC Criteria: January 27, 2017
• First Posted (Estimate): January 30, 2017

Study Record Updates

• Last Update Posted (Actual): September 28, 2018
• Last Update Submitted That Met QC Criteria: September 27, 2018
• Last Verified: September 1, 2018

More Information

Terms related to this study

• Keywords: motor development; Premature Baby; cognitive development
• Additional Relevant MeSH Terms: Pregnancy Complications; Obstetric Labor Complications; Obstetric Labor, Premature; Premature Birth
• Other Study ID Numbers: 11223 (FUNDESALUD)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED
• IPD Plan Description: We have no decided yet