Gut Microbiota and Stool Frequency

The Association Between Gut Microbiota and Stool Frequency

We hypothesized that some difference in the composition and distribution of gut microbiota in people with a large number of defecation (two or three times a day or more), people with normal defecation (one time a day or two days), and people with a small number of defecation (two times a week or less).

And we investigate the association between gut microbiota and stool frequency.

Study Overview

• Status: Completed
• Conditions: Gut Microbiota
• Intervention / Treatment: Other: Stool frequency

Detailed Description

We divided three groups. (total number = 60 subjects)

1. a large number of defecation group (≥ 2-3 times/day) - 20 subjects
2. normal defecation group (1 time/day or 1 time/2 days) - 20 subjects
3. a small number of defecation group (≤ 2 times/week) - 20 subjects

After collection of stools, we will analyze the composition and distribution of gut microbiota, and compared the results of three groups.

• Study Type: Observational
• Enrollment (Actual): 60

Contacts and Locations

Study Locations

• Korea, Republic of
  • Busan, Korea, Republic of, 49267
    • Kosin University Gospel Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 50 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Healthy volunteers

Description

Inclusion Criteria:

• adults between the age of 20 and 50

Exclusion Criteria:

• subjects with cancer or IBD (inflammatory bowel disease)
• subjects with history of abdominal surgery
• subjects who take medication related to gastrointestinal motility within 3 months
• subjects who take antibiotics within 3 months

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
group 1; a large number of defecation group (≥ 2-3 times/day) - 20 subjects	Other: Stool frequency; This study is just observational study.
group 2; normal defecation group (1 time/day or 1 time/2 days) - 20 subjects	Other: Stool frequency; This study is just observational study.
group 3; a small number of defecation group (≤ 2 times/week) - 20 subjects	Other: Stool frequency; This study is just observational study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
stool frequency and gut microbiota	Analysis of correlation between stool frequency and gut microbiota	six months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
stool consistency and gut microbiota	Analysis of correlation between stool consistency and gut microbiota	six months

Collaborators and Investigators

• Sponsor: Kosin University Gospel Hospital

Study record dates

Study Major Dates

• Study Start (Actual): May 11, 2017
• Primary Completion (Actual): September 30, 2017
• Study Completion (Actual): October 30, 2017

Study Registration Dates

• First Submitted: May 11, 2017
• First Submitted That Met QC Criteria: May 11, 2017
• First Posted (Actual): May 15, 2017

Study Record Updates

• Last Update Posted (Actual): December 4, 2017
• Last Update Submitted That Met QC Criteria: December 1, 2017
• Last Verified: December 1, 2017

More Information

Terms related to this study

• Keywords: gut microbiota; stool frequency
• Other Study ID Numbers: 2017-02-017-001

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: We have no plan to share IPD to other researchers.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No