Risk Factors for Predictors of In-hospital Death in Acute Fulminant Myocarditis

Risk Factors Influenced Prognosis of Acute Fulminant Myocarditis by Analyzing Clinical Characteristics and Complications, Laboratory Findings, Treatments, and Electrocardiographic and Echocardiographic Data.

The investigators performed a retrospective, single-center observational study, and the participants with acute fulminant myocarditis were included.Then, the investigator analyzed the risk factors of in-hospital death in these participants with acute fulminant myocarditis.

Study Overview

• Status: Completed
• Conditions: Risk Factor, Cardiovascular; Cardio-Renal Syndrome; Viral Myocarditis
• Intervention / Treatment: Other: prognosis

• Study Type: Observational
• Enrollment (Actual): 76

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The definition of a fulminant acute myocarditis was the presence of a rapid onset of aggressive life-threatening disease accompanied by cardiogenic shock with multiple organ dysfunction syndrome, acute severe heart failure, fatal arrhythmias, high-degree atrioventricular blockade, or sudden cardiac death following a flu-like illness.

Description

Inclusion Criteria:

Clinical diagnosis of acute fulminant myocarditis

Exclusion Criteria:

chronic renal dysfunction refuse medical treatments

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
non-survivor group	Other: prognosis; The participants were divided into two groups based on survival at their hospital discharge.
survivor group	Other: prognosis; The participants were divided into two groups based on survival at their hospital discharge.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Renal Impairment Influence Prognosis of Acute Fulminant Myocarditis	2017-01-30

Collaborators and Investigators

• Sponsor: The First Affiliated Hospital of Soochow University
• Investigators: Principal Investigator: Xiangjun Yang, PhD, First Affiliated Hospital of Soochow University

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2016
• Primary Completion (Actual): December 30, 2016
• Study Completion (Actual): December 30, 2016

Study Registration Dates

• First Submitted: July 4, 2017
• First Submitted That Met QC Criteria: July 14, 2017
• First Posted (Actual): July 18, 2017

Study Record Updates

• Last Update Posted (Actual): July 18, 2017
• Last Update Submitted That Met QC Criteria: July 14, 2017
• Last Verified: July 1, 2017

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Kidney Diseases; Urologic Diseases; Renal Insufficiency; Cardiomyopathies; Heart Failure; Myocarditis; Cardio-Renal Syndrome
• Other Study ID Numbers: myocarditis20161226

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No