- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03366259
Prostaglandins Before Caserean Section
December 7, 2017 updated by: sarah mohamed hassan, Kasr El Aini Hospital
Does the Administration of Prostaglandins Before Cesarean Section Reduce the Amount of Blood Loss ?
The aim of our study is to assess the value of administration of prostaglandins before cesarean section to reduce the amount of blood loss
Study Overview
Status
Unknown
Conditions
Intervention / Treatment
Detailed Description
160 full term pregnant patients candidate for elective cesarean section were randomly allocated into 2 groups ,80 patients will receive 200mcg of rectal prostaglandins before cesarean section and 80 patients are used as control receiving placebo
Study Type
Interventional
Enrollment (Anticipated)
160
Phase
- Phase 2
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Cairo, Egypt, 11562
- Kasr El Ainiy Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years to 40 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Description
Inclusion Criteria:pregnant patients full term elective cesarean section
-
Exclusion Criteria:
- medical disorder with pregnancy
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: Group A (Misoprostol group)
200 mcg rectal Misoprostol administration before cesarean section
|
administration of 200 Mcg of misoprotol rectal
elective cesarean section for full term patients
|
Placebo Comparator: Group B (control group)
No prostaglandins administration before cesarean section
|
elective cesarean section for full term patients
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
amount of intraoperative blood loss
Time Frame: during cesarean section
|
number of soaked towels
|
during cesarean section
|
postpartum hemorrhage
Time Frame: 24 hour after cesarean section
|
blood loss after cesarean section
|
24 hour after cesarean section
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
fetal condition
Time Frame: 5 minutes after cesarean section
|
apgar score
|
5 minutes after cesarean section
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Anticipated)
December 1, 2017
Primary Completion (Anticipated)
February 1, 2018
Study Completion (Anticipated)
February 1, 2018
Study Registration Dates
First Submitted
December 4, 2017
First Submitted That Met QC Criteria
December 4, 2017
First Posted (Actual)
December 8, 2017
Study Record Updates
Last Update Posted (Actual)
December 11, 2017
Last Update Submitted That Met QC Criteria
December 7, 2017
Last Verified
December 1, 2017
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 4122017
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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