Effectiveness of MIRT on Hand and Finger Dexterity in PD Patients (H_F_ D_PD_MIRT)

Aims of the study are (1) to evaluate the effectiveness of a specific OT treatment aimed to enhance finger and hand dexterity and (2) its impact on daily living autonomy of PD patients.

Study Overview

• Status: Completed
• Conditions: Parkinson Disease; Rehabilitation; Dexterity
• Intervention / Treatment: Behavioral: MIRT

Detailed Description

Reduction in hand functionality and finger dexterity are significant, but often overlooked, symptoms of Parkinson's Disease (PD). They are strictly correlated with loss of patient's autonomy, due to their significant impact on Activities of Daily Living (ADL) and, consequently in patient's Quality of life (QoL). No studies investigated the effectiveness of a specific and functional-based Occupational Therapy (OT) treatment in improving hand functionality and finger dexterity in PD patients.

Aims of tthe study are to evaluate the effectiveness of a specific OT treatment aimed to enhance finger and hand dexterity and its impact on daily living autonomy of PD patients.

Retrospectively, 482 PD patients, hospitalized for a 4-week Multidisciplinary Intensive Rehabilitation Treatment (MIRT) between January 2015 and January 2018 were identified. All patients underwent 1h/day OT treatment. The outcome measure was the O'Connor finger dexterity test; secondary outcome measures were Minnesota dexterity test, UPDRS II and SPDDS scale. These measures were assessed at admission (T0) and discharge (T1).

• Study Type: Observational
• Enrollment (Actual): 482

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Parkinsonian inpatients

Description

Inclusion Criteria:

• diagnosis of Parkinson's Disease

Exclusion Criteria:

• other neurological disease
• psychosis
• auditive or visual deficit

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
PD patients; PD patients at 1-5 H&Y stage undergoes 4week Multidisciplinary Intensive Rehabilitation Treatment	Behavioral: MIRT; 4 week MIRT provide: front to front treatment (1 hour/day for 5 days/week); treatment with robotic devices (1 hour/day for 5 days/week); occupational therapy (1 hour/day for 5 days/week); Other Names: Multidisciplinary Intensive Rehabilitation Treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
O'Connor Finger Dexterity Test	peg-placement test aimed to evaluate the ability to manipulate small objects	4 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Minnesota Manual Dexterity Test	test aimed to evaluate the reach-to-grasp movements, gros manual dexterity and left vs right manual impairment	4 weeks

Collaborators and Investigators

• Sponsor: Ospedale Generale Di Zona Moriggia-Pelascini

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2015
• Primary Completion (Actual): August 1, 2018
• Study Completion (Actual): August 1, 2018

Study Registration Dates

• First Submitted: November 26, 2018
• First Submitted That Met QC Criteria: December 2, 2018
• First Posted (Actual): December 4, 2018

Study Record Updates

• Last Update Posted (Actual): December 4, 2018
• Last Update Submitted That Met QC Criteria: December 2, 2018
• Last Verified: November 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Parkinsonian Disorders; Basal Ganglia Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Parkinson Disease
• Other Study ID Numbers: H_F_D_PD_MIRT

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No