- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04010409
Mindreading in Adults With Autism Spectrum Disorder
April 13, 2023 updated by: National Taiwan University Hospital
This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task.
We plan to recruit 50 adults with ASD and 50 typically-developing adults.
Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Detailed Description
Autism spectrum disorder (ASD) is a clinical syndrome characterized by mindreading deficits, or Theory of Mind deficits.
The Reading the Mind in the Eyes task (abbreviated as the Eyes task) was developed to assess the mindreading deficits as a hallmark of social deficits of ASD.
This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task.
We plan to recruit 50 adults with ASD and 50 typically-developing adults.
All the participants will complete clinical measures and the Eyes task.
Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.
Study Type
Observational
Enrollment (Anticipated)
60
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Yi Ling Chien, M.D., Ph.D.
- Phone Number: 66013 886-2-2312-3456
- Email: ylchien@hotmail.com
Study Locations
-
-
-
Taipei, Taiwan
- Recruiting
- National Taiwan University Hospital
-
Contact:
- Yi Ling Chien, M.D., Ph.D.
- Phone Number: 66013 886-2-2312-3456
- Email: ylchien@hotmail.com
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years to 50 years (Adult)
Accepts Healthy Volunteers
Yes
Sampling Method
Non-Probability Sample
Study Population
The 30 adults with ASD will be recruited from Adult ASD clinics in Department of Psychiatry, National Taiwan University Hospital.
Description
Inclusion Criteria:
- Adult aged between 20 and 50 years who had a diagnosis of ASD based on DSM-5.
- Had a full-scale IQ > 70 on WAIS-IV.
Exclusion Criteria:
- A history of major mental illness (e.g., bipolar affective disorder, schizophrenia) or neurological diseases.
- Visual impairment and that would preclude participation.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Case-Control
- Time Perspectives: Cross-Sectional
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
ASD Group
Autism spectrum disorder participants, no intervention
|
no intervention
|
TD Group
Typically developmental controls,no intervention
|
no intervention
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
eye tracking indicators
Time Frame: 30 min
|
eye tracking indicators
|
30 min
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Yi Ling Chien, M.D., Ph.D., National Taiwan University Hospital
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 8, 2019
Primary Completion (Anticipated)
December 31, 2024
Study Completion (Anticipated)
December 31, 2024
Study Registration Dates
First Submitted
July 4, 2019
First Submitted That Met QC Criteria
July 4, 2019
First Posted (Actual)
July 8, 2019
Study Record Updates
Last Update Posted (Actual)
April 18, 2023
Last Update Submitted That Met QC Criteria
April 13, 2023
Last Verified
December 1, 2022
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 201809069RINA
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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