Heat Acclimation, Hand Cooling Efficacy, and Adaptation Maintenance.

February 13, 2020 updated by: Douglas J Casa, University of Connecticut

The Effect of Heat Acclimation on Repeated Bouts of Strenuous Heat Stress, Hand Cooling Efficacy, and the Maintenance Thereof.

This study had three aims:

  1. To determine the impact of consecutive days of exercise on thermoregulation and cardiovascular strain.
  2. To determine the efficacy of a hand cooling device to cool individuals throughout a heat acclimation period.
  3. To assess the maintenance of thermoregulatory and cardiovascular adaptations derived from heat acclimation during a 25-day intermittent exercise-heat exposure protocol.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Participants completed 14 days of exercise heat acclimation in either a hot or cool environment, followed by a heat or cool exercise exposure every 5th day for 25 days. Cardiovascular, thermoregulatory, and perceptual strain were measured throughout exercise each day. Hydration assessment and stress response via blood biomarkers were measured before and after exercise. Aerobic capacity was measured before and after heat acclimation as well as after the intermittent exercise-heat exposure. Hand cooling was implemented periodically during exercise-heat stress visits to determine cooling efficacy before and after heat acclimation.

Study Type

Interventional

Enrollment (Actual)

34

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 35 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • no chronic health problems
  • no previous history of exertional heat stroke within the past 3 years
  • no history of cardiovascular, metabolic or respiratory disease
  • no current musculoskeletal injury that limits physical activity

Exclusion Criteria:

  • women
  • exercise less than once per week
  • VO2max < 45 ml/kg/min

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Exercise in heat group
Exercise in a hot environment
Other: Heat acclimation
14 days of aerobic exercise in a hot environment
Placebo Comparator: Exercise in cool group
Exercise in a cool environment
Other: Exercise in a cool environment
14 days of aerobic exercise in a cool environment

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Internal Body Temperature
Time Frame: 5 days
Rectal temperature was assessed five days following measurement at baseline.
5 days

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Heart Rate
Time Frame: 5 days
Heart rate was assessed five days following baseline.
5 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Connecticut

Investigators

  • Principal Investigator: Douglas J Casa, PhD, University of Connecticut

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 1, 2014

Primary Completion (Actual)

March 31, 2015

Study Completion (Actual)

March 31, 2015

Study Registration Dates

First Submitted

August 7, 2019

First Submitted That Met QC Criteria

August 9, 2019

First Posted (Actual)

August 12, 2019

Study Record Updates

Last Update Posted (Actual)

February 27, 2020

Last Update Submitted That Met QC Criteria

February 13, 2020

Last Verified

February 1, 2020

More Information

Terms related to this study

Other Study ID Numbers

  • H14-188

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Aggregate data can be shared upon request.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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