Effects of Motor Imagery in Pain Modulation and Median Nerve Mechanosensitive in Healthy Patients

The aim of this study are 1) to determinate the effectiveness of motor imagery or strength training in differens aspects of pain modulation. 2) evaluate the functional improvement of the hand by a motor imagery protocol.

Study Overview

• Status: Completed
• Conditions: Median Nerve Injury
• Intervention / Treatment: Other: Mirror therapy; Other: Neurodynamic exercises; Other: Strength; Other: Action observation

• Study Type: Interventional
• Enrollment (Actual): 100
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Spain
  • Madrid
    • Alcorcón, Madrid, Spain, 28922
      • Universidad Rey Juan Carlos

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Healthy

Exclusion Criteria:

• be under 18
• any pathology which provoke pain.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Action observation; The patients will observe a 25 minutes clip of neurodynamic exercises of the hand.	Other: Mirror therapy; With a mirror glasses on, do the neurodynamic exercises with the non-dominant hand while the patient is looking at the dominant hand; Other: Neurodynamic exercises; active movement of the dominant hand. Do neurodynamic exercises.; Other: Strength; Execute a short strength training for the dominant hand
Experimental: Mirror Therapy; With a mirror glasses, the patients will execute neurodynamic movements of their non-dominant hand during 25 minutes.	Other: Neurodynamic exercises; active movement of the dominant hand. Do neurodynamic exercises.; Other: Strength; Execute a short strength training for the dominant hand; Other: Action observation; look at a clip of a hand doing neurodynamic exercises.
Active Comparator: Strength Training; Strength protocol for the dominant hand.	Other: Mirror therapy; With a mirror glasses on, do the neurodynamic exercises with the non-dominant hand while the patient is looking at the dominant hand; Other: Neurodynamic exercises; active movement of the dominant hand. Do neurodynamic exercises.; Other: Action observation; look at a clip of a hand doing neurodynamic exercises.
Experimental: Neurodynamic exercise; Active neurodynamic exercises for the dominant hand.	Other: Mirror therapy; With a mirror glasses on, do the neurodynamic exercises with the non-dominant hand while the patient is looking at the dominant hand; Other: Strength; Execute a short strength training for the dominant hand; Other: Action observation; look at a clip of a hand doing neurodynamic exercises.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Conditioned pain modulation	Diffused noxious inhibitory control system will be measure with tourniquet test	Change from baseline at 2 weeks
Pressure pain threshold	Three consecutive trials of pressure pain threshold on the active trigger point at a rate of 1 kg/sec at intervals of 30 seconds were conducted.	Change from baseline at 2 weeks
Cold hyperalgesia	10 seconds of a cold pack and after that, rating the pain from 0 to 10	Change from baseline at 2 weeks
Neural mechanosensitive	Upper Limb Neurodynamic test 1 (ULNT1)	Change from baseline at 2 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Strength_grip	grip strength without pain	Change from baseline at 2 weeks
Imagine movement capacity	testing the capacity of imagine that their own body is movement. Movement Imagery Questionnaire-Revised (MIQ-R questionaire). top score 56 and bottom score 8. The higher values indicates a better outcome.	Change from baseline at 2 weeks
Psychological factors_Anxiety	State Trait Anxiety Inventory (STAI-T). Top score 60 and bottom score 0. The higher values indicate worst outcomes.	Change from baseline at 2 weeks
Psychological factors_Depression	Beck Depression Inventory (BDI-II). the scores goes from 0 to 63. The higher values indicate worst outcomes. Beck Depression Inventory (BDI-II) Beck Depression Inventory (BDI-II)	Change from baseline at 2 weeks
Psychological factors_Kinesiophobia	Tampa Scale for Kinesiophobia. Total scores goes from 11 to 44.The higher values indicate worst outcomes.	Change from baseline at 2 weeks

Collaborators and Investigators

• Sponsor: Universidad Rey Juan Carlos

Publications and helpful links

General Publications

• Matesanz-García L, Cáceres-Pajuelo JE, Cuenca-Martínez F, La Touche R, Goicoechea-García C, Fernández-Carnero J. Effects of neural mobilizations through movement representation techniques for the improvement of neural mechanosensitivity of the median nerve region: a randomized controlled trial. Somatosens Mot Res. 2021 Dec;38(4):267-276. doi: 10.1080/08990220.2021.1964463. Epub 2021 Aug 17.

Study record dates

Study Major Dates

• Study Start (Actual): September 8, 2019
• Primary Completion (Actual): January 31, 2020
• Study Completion (Actual): February 25, 2020

Study Registration Dates

• First Submitted: August 9, 2019
• First Submitted That Met QC Criteria: September 9, 2019
• First Posted (Actual): September 11, 2019

Study Record Updates

• Last Update Posted (Actual): June 8, 2021
• Last Update Submitted That Met QC Criteria: June 7, 2021
• Last Verified: June 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: 2703201906919

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No