Physical Activity Program for Counteracting Sarcopenia

Effects of an Home-base Physical Activity Program for Counteracting Sarcopenia in Elderly: a Randomized-controlled Trial.

Sponsors

Lead Sponsor: Istituto Ortopedico Galeazzi

Source Istituto Ortopedico Galeazzi
Brief Summary

Sarcopenia is a pathophysiological process associated with aging and some metabolic conditions characterized by progressive muscle tissue loss, which may lead to loss of strangth and performance and increase risk of falls and fractures, physical disability and premature death. Therefore, it is necessary to identify personalized programs of physical activity and supplementation for elderly population in order to improve their physical functions, muscle strengh and body composition.

With the present project we aime to assess the effect of a feasible home-based exercise program coupled with food supplementation to improve muscle strength, muscle volume and muscle physical performance potentially associated with sarcopenia in elderly people.

Overall Status Recruiting
Start Date September 18, 2019
Completion Date December 20, 2020
Primary Completion Date December 20, 2020
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Lower limb strength Week 12
Enrollment 36
Condition
Intervention

Intervention Type: Behavioral

Intervention Name: Physical activity

Description: Home-based physical activity program

Arm Group Label: Physical activity group

Intervention Type: Dietary Supplement

Intervention Name: Physical activity and supplementation

Description: Home-based physical activity program and amminoacid supplementation

Arm Group Label: Physical activity and supplementation group

Intervention Type: Other

Intervention Name: Control

Description: No intervention

Arm Group Label: Control group

Eligibility

Criteria:

Inclusion Criteria:

- Sedentary lifestyle.

- Cognitively intact.

- Autonomous walking.

- Acceptance of informed consent.

Exclusion Criteria:

- Body mass index lower than 18.5 and uppen than 40 kg/m2.

- History of cancer.

- Pacemaker user.

- History of epileptic episodes.

- Endocrine-metabolic, neurological, muscular and ortopedic pathologies that affect movement functions.

- Bone fractures that influence movement functions.

- Smoking.

- Surgical treatments in the prior 6 months.

- Use of antieptilectics, glucocorticoids, rhGH and testosterone.

- Hepatic and muscular pathologies

Gender: All

Minimum Age: 60 Years

Maximum Age: 80 Years

Healthy Volunteers: Accepts Healthy Volunteers

Overall Contact

Last Name: Matteo Bonato, Ph.D.

Phone: 00390266214980

Email: [email protected]

Location
Facility: Status: Contact: IRCCS Istituto Ortopedico Galeazzi Elena Cittera 00390266214057 [email protected]
Location Countries

Italy

Verification Date

November 2019

Responsible Party

Type: Sponsor

Has Expanded Access No
Condition Browse
Number Of Arms 3
Arm Group

Label: Physical activity group

Type: Experimental

Label: Physical activity and supplementation group

Type: Experimental

Label: Control group

Type: Experimental

Acronym EXERSARCO
Study Design Info

Allocation: Randomized

Intervention Model: Parallel Assignment

Primary Purpose: Treatment

Masking: Single (Participant)

Source: ClinicalTrials.gov