- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04237363
Recovery of Walking in Persons With Complete Spinal Cord Injury
January 17, 2020 updated by: Middle Tennessee State University
Recovery of Walking Without Epidural Spinal Cord Stimulation in Adults With Complete Spinal Cord Injury
We documented the impact of 1 year of underwater treadmill training and supplemental overground walk training in five adults with chronic motor-complete SCI (cSCI) who had not undergone programmed epidural spinal cord stimulation (eSCS).
Study Overview
Detailed Description
Regular exposure to self-initiated treadmill walking in water, a unique sensorimotor exercise setting that makes stepping movements easier to perform, may capitalize on the adaptability of the neuromuscular system and enhance locomotor function in persons with cSCI who have not undergone eSCS.
In our study, a combined aquatics- and land-based approach to gait training was employed over a 12-month period that featured underwater treadmill training and supplemental overground walk training.
Study Type
Interventional
Enrollment (Actual)
5
Phase
- Not Applicable
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
21 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria
- At least 21 years of age
- Presence of traumatic or non-traumatic spinal cord injury for at least 1 year
- Medical diagnosis of paraplegia (T1 or below)
Exclusion Criteria
- Presence of complex comorbidities that could limit involvement in training activities
- Surgical implantation or removal of a medical device six months prior to training
- Skin breakdown
- Use of electrical implants to promote ambulation
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Exercise
Walk training
|
Underwater treadmill training and supplemental overground walk training
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Overground walking capacity
Time Frame: Change from Baseline WISCI-II score at 6 months and 12 months
|
Walking Capacity for Spinal Cord Injury (WISCI-II)
|
Change from Baseline WISCI-II score at 6 months and 12 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Study Director: Don W Morgan, PhD, Middle Tennessee State University
- Principal Investigator: Sandra L Stevens, PhD, PT, Middle Tennessee State University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
July 5, 2011
Primary Completion (Actual)
August 6, 2013
Study Completion (Actual)
August 6, 2013
Study Registration Dates
First Submitted
January 15, 2020
First Submitted That Met QC Criteria
January 17, 2020
First Posted (Actual)
January 23, 2020
Study Record Updates
Last Update Posted (Actual)
January 23, 2020
Last Update Submitted That Met QC Criteria
January 17, 2020
Last Verified
January 1, 2020
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 11-310
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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