Profile of Pediatric Patients Admitted to AU ICU

Profile and Clinical Outcome of Pediatric Patients Admitted to Intensive Care Unit of Assiut University Children Hospital

This study aims to determine the profile and outcome of children admitted to ICU at Assiut University children hospital in order to detect association between risk factors and outcome, to asses the efficacy of treatment making it possible to take better decisions , to improve the quality of care.

Study Overview

• Status: Unknown
• Conditions: Critical Illness
• Intervention / Treatment: Other: Demographic data, morbidity data

• Study Type: Observational
• Enrollment (Anticipated): 100

Contacts and Locations

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 1 month to 18 years (ADULT, CHILD)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients admitted to the PICU whichever is the diagnosis

Description

Inclusion Criteria:

• all patients admitted to intensive care unit of Assiut University children hospital over one year aged from 1month to 18 years

Exclusion Criteria:

• pediatric patients less than one month old Pediatric patients will die on arrival

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients according to age groups and gender	The demographic data (including age groups and gender). Regarding age groups, the number of patients in each of three groups will be addressed: 1 month to 2 years of age; 2 years to 12 years of age; 12 to 18 years of age" Regarding gender, the number of patients will be allocated in 2 groups: male; female	1 year
Number of patients according to diagnosis on admission	Provisional diagnosis on admission categorised by the system affected (respiratory, cardiovascular, neurological, hematological, renal, endocrinal and metabolic gastrointestinal and hepatobiliary, multi system affection, others (post operative, post arrest, sepsis syndrome, malignancies, poisoning, coma of unknownorigin)). The data will be presented as number of patients in each group of system affected.	1 year
Number of patients according to referral site	The patients will be allocated in 2 groups of referral sites of patients admitted to the PICU: the ward; the emergency department. Data will be presented as number of patients in each group.	1 year
Number of patients according to the need for mechanical ventilation and its duration	The patients will be allocated in 2 groups based on the need for mechanical ventilation duringthe PICU stay. In case of need for mechanical ventilation, the duration will be recorded in days.	1 year
Length of stay in days	Length of stay in the pediatric intensive care unit (PICU) will be presented as number of days spent by the patient from admission to discharge or death.	1 year
Pediatric Risk of Mortality score on admission	Pediatric Risk of Mortlaity (PRISM) III score will be obtained from all patients within the first 24 hours of admission to the PICU. The maximum total PRISM III score is 74. The higher the score, the worse the prognosis. For the analysis of mortality risk factors, patients will be allocated into two groups according to PRISM III 24 score values >8 and ≤ 8, based on previously published data showing increased mortality risk in patients with PRISM III 24 score >8.	1 year
Number of patients according to the condition of discharge from the pediatric intensive care unit	Number of patients discharged from the PICU allocated in 2 groups: improvent and transfer to the corresponding medical ward. (Survivors); death. N.B. patients who will be discharged against medical advice (DAMA) will be excluded from the proposed data analysis, but will be pointed at.	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Correlation 1	Correlation between number of patients in discharge groups (survivors / dead) and age group.	1 year
Correlation 2	Correlation between number of patients in discharge groups (survivors / dead) and diagnosis on admission.	1 year
Correlation 3	Correlation between number of patients in discharge groups (survivors / dead) and length of stay.	1 year
Correlation 4	Correlation between number of patients in discharge groups (survivors / dead) and PRISM III score.	1 year
Correlation 5	Correlation between number of patients in discharge groups (survivors / dead) and duration of mechanical ventilation.	1 year

Collaborators and Investigators

• Sponsor: Assiut University

Publications and helpful links

General Publications

• Haftu H, Hailu T, Medhaniye A, G/Tsadik T. Assessment of pattern and treatment outcome of patients admitted to pediatric intensive care unit, Ayder Referral Hospital, Tigray, Ethiopia, 2015. BMC Res Notes. 2018 May 24;11(1):339. doi: 10.1186/s13104-018-3432-4.
• Khilnani P, Sarma D, Singh R, Uttam R, Rajdev S, Makkar A, Kaur J. Demographic profile and outcome analysis of a tertiary level pediatric intensive care unit. Indian J Pediatr. 2004 Jul;71(7):587-91. doi: 10.1007/BF02724117.

Study record dates

Study Major Dates

• Study Start (ANTICIPATED): April 1, 2020
• Primary Completion (ANTICIPATED): March 30, 2021
• Study Completion (ANTICIPATED): May 1, 2021

Study Registration Dates

• First Submitted: March 19, 2020
• First Submitted That Met QC Criteria: March 25, 2020
• First Posted (ACTUAL): March 27, 2020

Study Record Updates

• Last Update Posted (ACTUAL): March 27, 2020
• Last Update Submitted That Met QC Criteria: March 25, 2020
• Last Verified: March 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Critical Illness
• Other Study ID Numbers: gehad011157

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No