Laser in Orthodontic Leveling and Alignment

Outcome of Low-level Laser Therapy Regarding Orthodontic Leveling and Alignment of Mandibular Anterior Segment: A Controlled Clinical Appraisal

to evaluate the outcome of LLLT regarding leveling and alignment of the mandibular anterior segment.

Study Overview

• Status: Completed
• Conditions: Dental Malocclusion
• Intervention / Treatment: Radiation: low level laser therapy

Detailed Description

Thirty patients, 18 females and 12 males, were included who had Class I malocclusion with moderate mandibular crowding and an average age was 19.23 ± 3.1years.They were randomly divided into two parallel groups; a control group without laser intervention and a laser group which received LLLT. All patients followed a non-extraction approach using one category of fixed appliance and matching conventional NiTi archwire sequence during 3 months observation period. In laser group, mandibular anterior teeth were irradiated by gallium aluminum arsenide semiconductor laser with 635 nm wavelength, 6.5J/cm2energy density, for 10 seconds at 10 points (0.2 J/point) on facial and lingual aspects. This protocol was started immediately after first wire insertion and then at days 3,7,14 of the first month and repeated for additional 2 months. In both groups, relief of mandibular crowding was assessed by Little's irregularity index (LII) after 4 weeks (T1), after 8 weeks (T2), and after 12 weeks (T3) intervals. Changes in LII scores were evaluated through scanned 3D models via software. In addition, the monthly rate of OTM was calculated and compared. The level of significance was set at p ≤ 0.05.

• Study Type: Interventional
• Enrollment (Actual): 26
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt, 11751
    • Al-Azhar University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 16 years to 25 years (Child, Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Selection of participants was based on the following criteria:

  1. The age range was from 15 to 25 years.
  2. All permanent teeth erupted (3rd molar not included).
  3. Angle class I occlusion with normal facial proportions.
  4. Moderate crowding in the lower dental arch assessed by Little's irregularity index that requires treatment with fixed appliance using non-extraction approach.
  5. Good oral and general health.
  6. No previous or current periodontal disease.
  7. No systemic disease or regular medication that could interfere and\or affects orthodontic teeth movement.
  8. No evidence of craniofacial anomalies, such as cleft lip and palate or previous history of trauma, bruxism or parafunction.
  9. No previous orthodontic treatment.

Exclusion Criteria:

• The patients were excluded from the study if they have:

  1. Severe crowding that requires an extraction approach.
  2. Blocked-out teeth that didn't allow for placement of the bracket at the initial bonding appointment.
  3. Poor oral hygiene or periodontally compromised teeth.
  4. Relevant medical history that interferes with orthodontic treatment.
  5. Craniofacial anomalies or previous history of trauma, bruxism or parafunction.
  6. Previous orthodontic treatment.
  7. The deep bite which interferes with orthodontic brackets placement.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: control group; was treated without laser intervention
Experimental: laser group; received low level laser therapy	Radiation: low level laser therapy; mandibular anterior teeth were irradiated by gallium aluminum arsenide semiconductor laser with 635 nm wavelength, 6.5J/cm2energy density, for 10 seconds at 10 points (0.2 J/point) on facial and lingual aspects. This protocol was started immediately after first wire insertion and then at days 3,7,14 of the first month and repeated for additional 2 months; Other Names: photobiomodulation

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Evaluation of the alignment rate of the mandibular anterior segment with and without low level laser therapy	Effect of the LLLT on alignment of the mandibular anterior teeth through evaluation of changes in Little's Irregularity Index (LII) scores (mm) throughout 12 weeks observation period of the study	6 Months

Collaborators and Investigators

• Sponsor: Tharwat osman Mohi Eldeen Elshehawy
• Investigators: Principal Investigator: tharwat O elshehay, MSc student, Al-Azhar University

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2018
• Primary Completion (Actual): June 10, 2018
• Study Completion (Actual): July 15, 2018

Study Registration Dates

• First Submitted: May 2, 2020
• First Submitted That Met QC Criteria: May 3, 2020
• First Posted (Actual): May 6, 2020

Study Record Updates

• Last Update Posted (Actual): May 6, 2020
• Last Update Submitted That Met QC Criteria: May 3, 2020
• Last Verified: May 1, 2020

More Information

Terms related to this study

• Keywords: Low-level laser therapy; Orthodontic Tooth Movement; Leveling and Alignment; Little Irregularity Index.
• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Malocclusion
• Other Study ID Numbers: 101 (Hamilton Integrated Research Ethics Board)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No