Colonoscopy is an Aerosol Generating Procedure

Colonoscopy is an Aerosol-generating Procedure and Water-immersion Technique May Decrease the Amount of Aerosol Generated

With a commercially available particle counter, we can differentiate the particle counts of different sizes in different areas of the endoscopy room. An increase from baseline particles of < 5um during or after the procedure would suggest that the procedure is an AGP.

In this study, the particle counter from Met One Instruments model GT-526S will be used. A particle sizer is placed within 10cm of the anus, at the level of the endoscopists' face and at the level of the endoscopy nurse assistant's face The change in the particles of different sizes would be simultaneously recorded. The results of these three locations are compared to baseline and compared with each other

Study Overview

• Status: Unknown
• Conditions: To See if Colonoscopy is an Aerosol-generating Procedure and to Identify Ways to Minimise the Aerosol Generated
• Intervention / Treatment: Other: Particle counter

Detailed Description

Currently, the term droplet is often taken to refer to droplets >5 microns (μm) in diameter that fall rapidly to the ground under gravity, and therefore are transmitted only over a limited distance (e.g. ≤1 m). In contrast, the term droplet nuclei refers to droplets ≤5 μm in diameter that can remain suspended in air for significant periods of time, allowing them to be transmitted over distances >1 metre. With a commercially available particle counter, we can differentiate the particle counts of different sizes in different areas of the endoscopy room. An increase from baseline particles of < 5um during or after the procedure would suggest that the procedure is an AGP.

In this study, the particle counter from Met One Instruments model GT-526S will be used. The study will be conducted in the Prince of Wales Hospital endoscopy centre. A particle sizer is placed within 10cm of the anus, at the level of the endoscopists' face and at the level of the endoscopy nurse assistant's face The change in the particles of different sizes would be simultaneously recorded. The results of these three locations are compared to baseline and compared with each other.

• Study Type: Observational
• Enrollment (Anticipated): 120

Contacts and Locations

Study Locations

• Hong Kong
  • Hong Kong, Hong Kong, 00000
    • Recruiting
    • Prince of Wales Hospital
    • Contact: Shannon M Chan, FRCS; Phone Number: 852-35052627; Email: shannonchan@surgery.cuhk.edu.hk

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: ADULT; OLDER_ADULT; CHILD
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients who are planned for colonoscopy in the Prince of Wales Hospital, Hong kong.

Description

Inclusion Criteria:

- All patients who are planned for colonoscopy in the Prince of Wales Hospital, Hong kong

Exclusion Criteria:

• Patients where a flexible sigmoidoscopy was plannned Patients where the procedure was done in a negative pressure room Patients where the procedure was done in an endoscopy room other than the designated rooms Patients where the procedure was done under general anaesthesia

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Concentration of aerosol generated during the procedure	Concentration of aerosol generated during the procedure	During the procedure

Collaborators and Investigators

• Sponsor: Chinese University of Hong Kong
• Investigators: Principal Investigator: Shannon M Chan, FRCSEd, Chinese University of Hong Kong

Study record dates

Study Major Dates

• Study Start (ACTUAL): June 1, 2020
• Primary Completion (ANTICIPATED): December 30, 2020
• Study Completion (ANTICIPATED): January 31, 2021

Study Registration Dates

• First Submitted: July 17, 2020
• First Submitted That Met QC Criteria: July 17, 2020
• First Posted (ACTUAL): July 21, 2020

Study Record Updates

• Last Update Posted (ACTUAL): July 21, 2020
• Last Update Submitted That Met QC Criteria: July 17, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Keywords: Colonoscopy; Aerosol-generating procedure
• Other Study ID Numbers: 2020.200.2

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No