Prevalence Of COVID-19 Among Health-workers in a French General Hospital (POCAH-COVID)

September 14, 2020 updated by: Centre Hospitalier Sud Essonne
The aim of this study is to evaluate the prevalence of COVID-19 among the workers of our hospital and the factors that are likely to influence this prevalence. It must be underlined that our hospital is settled in two towns and both hospital sites had different missions regarding the admissions of COVID-19-infected patients.

Study Overview

Status

Unknown

Conditions

Detailed Description

Since December 2019, the COVID-19 pandemic has widespread from China and put under strong tension the health organizations throughout the world, especially since march 2020 in France.

As a consequence, the French hospitals had to cope with a massive amount of COVID-19 infected patients and, thus, their organisations had to evolve in order to be able to admit more patients in their critical care units.

First studies reported an important level of inter-human contagiousness of the SARS-CoV-2 virus with an "R0" (basic reproduction number) superior to 3, which could lead to a massive contamination of healthcare workers since they are directly in charge of infected patients.

Other studies suggested that the healthcare workers are more likely to be contaminated by the COVID-19 than the rest of the population, which pushed governments and hospital managers to put in place individual and collective measures of protection in order to avoid nosocomial transmissions and also to preserve the health of the hospital staffs in a context of high tension on the hospital work force.

There are today few data about the contamination level among the healthcare workers of general hospitals in France and about the severity of these contaminations. A national study is being conducted but on a macroscopic regional scale. In addition to that, the proportion of asymptomatic SARS-CoV-2 contaminated healthcare workers is not known as well as the origin (hospital or community) of the contaminations.

In June 2020, the French Health Ministry decided to launch a collection of epidemiological data in the French hospitals based on serologic tests. Thanks to this action and with the results of all the RT PCR tests systematically conducted since the beginning of the pandemic when a healthcare worker had COVID-19-like symptoms, the Centre Hospitalier Sud Essonne has decided to conduct an observational study.

The aim of this study is to evaluate the prevalence of COVID-19 among the workers of our hospital and the factors that are likely to influence this prevalence. It must be underlined that our hospital is settled in two towns and both hospital sites had different missions regarding the admissions of COVID-19-infected patients.

Study Type

Observational

Enrollment (Anticipated)

1300

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

N/A

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Adult healthcare workers who are not opposed to participate to the research

Description

Inclusion criteria:

  • hospital staff working at the Centre Hospitalier Sud Essonne,
  • employed by the Centre Hospitalier Sud Essonne between March, 5th, 2020, and August, 31rst, 2020,
  • with the result of an RT PCR test or a serologic test,
  • this (these) result(s) must have been/be communicated to the occupational health service of the hospital.

Exclusion criteria:

  • interim workers,
  • workers in holidays during the entire period of inclusion above,
  • opposition to participate in this study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
General prevalence of COVID-19
Time Frame: Through study completion, an average of 9 months

measures the prevalence of COVID-19 among the healthcare workers of the Centre Hospitalier Sud Essonne, defined as the hospital employees with positive serologic or RT-PCR tests.

It must be underlined that the notion of "health workers" include the entire hospital staff ie doctors, nurses, administrative employees,...

Through study completion, an average of 9 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of asymptomatic healthcare workers
Time Frame: Through study completion, an average of 9 months
  • no RT PCR or negative RT PCR and positive serologic test,
  • positive RT PCR and no symptoms,
Through study completion, an average of 9 months
Number of symptomatic healthcare workers
Time Frame: Through study completion, an average of 9 months
Positive RT-PCR test or serologic test with symptoms.
Through study completion, an average of 9 months
Number of healthcare workers with a severe form of COVID-19 which led to an hospitalization
Time Frame: Through study completion, an average of 9 months
Positive serologic or RTC-PCR test and hospitalization
Through study completion, an average of 9 months
Number of healthcare workers infected with COVID-19 and hospitalized in a critical care unit
Time Frame: Through study completion, an average of 9 months
Positive serologic or RTC-PCR test and hospitalization in a critical care unit
Through study completion, an average of 9 months
Influencing factors of the prevalence of the COVID-19 among healthcare workers
Time Frame: Through study completion, an average of 9 months
  • age,
  • gender,
  • job,
  • duration of employment in the hospital,
  • hospital site of affectation,
  • unit of affectation.
Through study completion, an average of 9 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Delphine LEMAIRE-BRUNEL, Centre Hospitalier Sud Essonne

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 3, 2020

Primary Completion (Anticipated)

April 30, 2021

Study Completion (Anticipated)

June 30, 2021

Study Registration Dates

First Submitted

September 7, 2020

First Submitted That Met QC Criteria

September 14, 2020

First Posted (Actual)

September 16, 2020

Study Record Updates

Last Update Posted (Actual)

September 16, 2020

Last Update Submitted That Met QC Criteria

September 14, 2020

Last Verified

September 1, 2020

More Information

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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