- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04548908
Prevalence Of COVID-19 Among Health-workers in a French General Hospital (POCAH-COVID)
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Since December 2019, the COVID-19 pandemic has widespread from China and put under strong tension the health organizations throughout the world, especially since march 2020 in France.
As a consequence, the French hospitals had to cope with a massive amount of COVID-19 infected patients and, thus, their organisations had to evolve in order to be able to admit more patients in their critical care units.
First studies reported an important level of inter-human contagiousness of the SARS-CoV-2 virus with an "R0" (basic reproduction number) superior to 3, which could lead to a massive contamination of healthcare workers since they are directly in charge of infected patients.
Other studies suggested that the healthcare workers are more likely to be contaminated by the COVID-19 than the rest of the population, which pushed governments and hospital managers to put in place individual and collective measures of protection in order to avoid nosocomial transmissions and also to preserve the health of the hospital staffs in a context of high tension on the hospital work force.
There are today few data about the contamination level among the healthcare workers of general hospitals in France and about the severity of these contaminations. A national study is being conducted but on a macroscopic regional scale. In addition to that, the proportion of asymptomatic SARS-CoV-2 contaminated healthcare workers is not known as well as the origin (hospital or community) of the contaminations.
In June 2020, the French Health Ministry decided to launch a collection of epidemiological data in the French hospitals based on serologic tests. Thanks to this action and with the results of all the RT PCR tests systematically conducted since the beginning of the pandemic when a healthcare worker had COVID-19-like symptoms, the Centre Hospitalier Sud Essonne has decided to conduct an observational study.
The aim of this study is to evaluate the prevalence of COVID-19 among the workers of our hospital and the factors that are likely to influence this prevalence. It must be underlined that our hospital is settled in two towns and both hospital sites had different missions regarding the admissions of COVID-19-infected patients.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Delphine LEMAIRE-BRUNEL
- Phone Number: +33 01 60 80 79 88
- Email: dlemaire-brunel@ch-sudessonne.fr
Study Locations
-
-
-
Etampes, France, 91150
- Recruiting
- Centre Hospitalier Sud Essonne
-
Contact:
- Delphine LEMAIRE-BRUNEL
- Phone Number: + 33 01 60 80 79 88
- Email: dlemaire-brunel@ch-sudessonne.fr
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion criteria:
- hospital staff working at the Centre Hospitalier Sud Essonne,
- employed by the Centre Hospitalier Sud Essonne between March, 5th, 2020, and August, 31rst, 2020,
- with the result of an RT PCR test or a serologic test,
- this (these) result(s) must have been/be communicated to the occupational health service of the hospital.
Exclusion criteria:
- interim workers,
- workers in holidays during the entire period of inclusion above,
- opposition to participate in this study.
Study Plan
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Prospective
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
General prevalence of COVID-19
Time Frame: Through study completion, an average of 9 months
|
measures the prevalence of COVID-19 among the healthcare workers of the Centre Hospitalier Sud Essonne, defined as the hospital employees with positive serologic or RT-PCR tests. It must be underlined that the notion of "health workers" include the entire hospital staff ie doctors, nurses, administrative employees,... |
Through study completion, an average of 9 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Number of asymptomatic healthcare workers
Time Frame: Through study completion, an average of 9 months
|
|
Through study completion, an average of 9 months
|
Number of symptomatic healthcare workers
Time Frame: Through study completion, an average of 9 months
|
Positive RT-PCR test or serologic test with symptoms.
|
Through study completion, an average of 9 months
|
Number of healthcare workers with a severe form of COVID-19 which led to an hospitalization
Time Frame: Through study completion, an average of 9 months
|
Positive serologic or RTC-PCR test and hospitalization
|
Through study completion, an average of 9 months
|
Number of healthcare workers infected with COVID-19 and hospitalized in a critical care unit
Time Frame: Through study completion, an average of 9 months
|
Positive serologic or RTC-PCR test and hospitalization in a critical care unit
|
Through study completion, an average of 9 months
|
Influencing factors of the prevalence of the COVID-19 among healthcare workers
Time Frame: Through study completion, an average of 9 months
|
|
Through study completion, an average of 9 months
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Delphine LEMAIRE-BRUNEL, Centre Hospitalier Sud Essonne
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- POCAH-COVID19
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Covid19
-
Anavasi DiagnosticsNot yet recruiting
-
Ain Shams UniversityRecruiting
-
Israel Institute for Biological Research (IIBR)Completed
-
Colgate PalmoliveCompleted
-
Christian von BuchwaldCompleted
-
Luye Pharma Group Ltd.Shandong Boan Biotechnology Co., LtdActive, not recruiting
-
University of ZurichLabor Speiz; Swiss Armed Forces; Universitätsspital ZürichEnrolling by invitation
-
Alexandria UniversityCompleted
-
Erasmus Medical CenterUniversity Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaboratorsRecruiting
Clinical Trials on Serelogy testing, RT PCR
-
Centre Hospitalier Sud EssonneRecruiting
-
Centre Hospitalier Universitaire VaudoisCompletedSARS-CoV-2Switzerland
-
King Fahad Specialist Hospital DammamUnknown
-
Central Hospital, Nancy, FranceRecruitingSARS-CoV2 Infection | Proximal Tubule DysfunctionFrance
-
The University of Hong KongWithdrawn
-
Oswaldo Cruz FoundationNational Institute of Allergy and Infectious Diseases (NIAID); Wellcome Trust; Walter Reed Army Institute of Research (WRAIR) and other collaboratorsCompleted
-
Sher-E-Bangla Medical CollegeRecruitingTo Assess Long-term Effects of COVID-19 in Patients Who Were Affected With COVID -19Bangladesh
-
Port Said UniversityUnknownPositive COVID-19 by PCREgypt
-
Ambry GeneticsCrozer-Keystone Health System; St. Joseph Hospital of Orange; The Saratoga HospitalCompleted
-
Centre de l'arthrose, ParisBeaujon HospitalCompleted