Eating Disorders and Autism Spectrum Disorders

March 15, 2023 updated by: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Characterization and Relationship Between Eating Disorders and Autism Spectrum Disorders.

This is an observational study where patients with eating disorders (ED) are compared with healthy controls without eating disorder (HC) regarding eating disorders features and autism spectrum features. Also patients will be reassessed after 5 years.

Study Overview

Status

Recruiting

Conditions

Detailed Description

The first author who suggested that eating disorders (EAD) and autism spectrum disorders (ASD) share common features was Christopher Gilberg in 1980. Currently it is known that patients with ED have social impairment, which is also a risk marker to develop ED, eating disturbances are overrepresented in ASD, ED and ASD have common behavioural features such as rigidity, perfectionism, and harm avoidance; and common cognitive profiles such as inflexibility, high attention to detail, high scores in systemizing profiles and poor results in advanced theory of mind tests. This relationship is also supported by similar neural phenotypes such as atypical structure and function in social brain regions found in both disorders.

The aim of the present study is to explore the relationship between ED and ASD traits in a sample of Spanish participants diagnosed with AN, bulimia nervosa (BN), binge-eating disorder (BED) and other eating disorders (OED). Specifically, the investigators aim to explore possible differences within the different ED and its particular transdiagnostic features in association with autistic traits.

The sample will consist of 90 patients with ED and 45 healthy controls (HC) without any current or lifetime history of mental disorder, both groups will be compared regarding ED and ASD features. Also patients will be reassessed in a 5 year follow up.

Study Type

Observational

Enrollment (Anticipated)

135

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

N/A

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients with ED and HC without ED.

Description

Inclusion Criteria:

  • Being Diagnosed with ED

Exclusion Criteria:

  • language or intellectual impairment

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
ED
Patients with Eating Disorders
HC
Healthy Controls without eating disorders

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Autism Spectrum Quotient
Time Frame: one year
A self report measure of autism traits. Its values range from 0 to 50. Higher scores mean higher autistic traits.
one year
Eating Disorders Inventory
Time Frame: one year
A self report measure of Eating Disorders characteristics. Its values range from 0 to 192, higher values mean higher eating disorders symptomatology.
one year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Bulimic Investigatory Test Edinburgh
Time Frame: one year
A self report measure of bulimic symptoms where higher scores mean more bulimic symptomatology. Scores range from 0 and 78.
one year
Quality of Life Enjoyment and Satisfaction Questionnaire
Time Frame: one year
The Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) is a self-report measure designed to enable investigators to easily obtain sensitive measures of the degree of enjoyment and satisfaction experienced by subjects in various areas of daily functioning. Its values range from 93 to 465. Higher values mean higher quality of life.
one year
Beck Depression Inventory
Time Frame: one year
a self report measure of depression symptomatology. Scores rang form 0 to 63, higher scores mean more depressive symptomatology.
one year
Scale Unawareness of Mental Disorders.
Time Frame: one year
A scale to asess awareness of mental disorders where higher punctuation mean higher levels of unawareness of the disorder. Scores range from 20 to 100.
one year
Body Shape Questionnaire
Time Frame: one year
A a self-report measure of the body shape preoccupations typical of bulimia nervosa and anorexia nervosa. Higher scores mean higher concern with shape. Score range from 34 to 204.
one year
Rosenberg Self -Esteem Scale
Time Frame: one year
A self report measure of self esteem. Its scores range from 10 to 40 where higher scores mean higher self -esteem
one year
State Trait Anxiety Inventory
Time Frame: one year
A self report measure of anxiety symptomatology. It has two scores one for state of anxiety and another for trait of anxiety, each subscale values range from 0 to 60, higher scores mean higher state or trait of anxiety.
one year
Inventory of interpersonal problems personality disorder
Time Frame: one year
A self report measure which is used to identify problems associated with particular personality disorders. Its values range from 0 to 256, higher scores mean higher interpersonal problems.
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 1, 2020

Primary Completion (Actual)

September 1, 2021

Study Completion (Anticipated)

December 1, 2025

Study Registration Dates

First Submitted

September 21, 2020

First Submitted That Met QC Criteria

September 21, 2020

First Posted (Actual)

September 25, 2020

Study Record Updates

Last Update Posted (Actual)

March 16, 2023

Last Update Submitted That Met QC Criteria

March 15, 2023

Last Verified

March 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IIBSP-TCA-2020-11

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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