Comparison of On-hours Versus Off-hours Anesthesia of Hip Surgery

August 20, 2021 updated by: Wei Mei, Huazhong University of Science and Technology

Comparison of Anesthesia Beginning at On-hours Versus Off-hours on Outcomes in Patients Undergoing Hip Surgery

To explore the impact of the begin time of anesthesia on in-hospital mortality and early prognosis of patients undergoing hip surgery.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The patients undergoing hip surgery between were divided into the on-hours group or the off-hours group depending on the begin time of anesthesia in this retrospective cohort study. In-hospital mortality and early prognosis were compared between the two groups.

Study Type

Observational

Enrollment (Actual)

1843

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Hubei
      • Wuhan, Hubei, China, 430030
        • Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients who had hip surgery during on-hours or off-hours.

Description

Inclusion Criteria:

  • All patients who had hip surgery between January 1, 2015, and December 31, 2020 in Tongji Hospital.

Exclusion Criteria:

  • under 18 years old
  • had incomplete perioperative data

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Retrospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
on-hours
Hip surgeries with the start time of anesthesia between 8:00 and 17:59 were coded as "on-hours".
Other: on-hours
If the begin time of anesthesia was between 8:00 to 17:59, it was defined as "on-hours".
off-hours
Hip surgeries with anesthesia beginning between 18:00 and 7:59 were coded as "off-hours". Besides, taking the long duration of hip surgery into account, if the anesthesia began before 18:00 but ended after 20:00, it was also defined as "off-hours".
Other: off-hours
If the start time of anesthesia was between 18:00 to 7:59 or the end time of anesthesia was later than 20:00, it was defined as "off-hours".

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
in-hospital mortality
Time Frame: up to 7 months
the mortality during hospitalization
up to 7 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
postoperative LOS
Time Frame: up to 4 months postoperatively
postoperative hospital length of stay
up to 4 months postoperatively
total LOS
Time Frame: up to 7 months
total hospital length of stay
up to 7 months
ICU admission
Time Frame: within 3 days postoperatively
the ratio of ICU admission
within 3 days postoperatively
postoperative complications
Time Frame: within 3 days postoperatively
including renal dysfunction, anemia, hypotension, deep vein thrombosis, arrhythmia, coronary artery disease or heart failure, pulmonary infection, electrolyte disturbance, hyoxemia and delirium
within 3 days postoperatively
intraoperative fluid management
Time Frame: intraoperative
including blood loss, urine volume, concentrated red blood cells, fresh frozen plasma, equilibrium liquid and colloidal solution
intraoperative
intraoperative sufentanil
Time Frame: intraoperative
the dosage of intraoperative sufentanil
intraoperative
using vasoactive drugs
Time Frame: intraoperative
whether using vasoactive drugs or not intraoperatively
intraoperative

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Huazhong University of Science and Technology

Investigators

  • Principal Investigator: Wei Mei, Tongji Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 2, 2021

Primary Completion (Actual)

August 8, 2021

Study Completion (Actual)

August 20, 2021

Study Registration Dates

First Submitted

June 21, 2021

First Submitted That Met QC Criteria

June 30, 2021

First Posted (Actual)

July 12, 2021

Study Record Updates

Last Update Posted (Actual)

August 23, 2021

Last Update Submitted That Met QC Criteria

August 20, 2021

Last Verified

August 1, 2021

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • TJ-IRB20210305

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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