Multisensory Training in PD

August 26, 2021 updated by: Yea-Ru Yang, National Yang Ming University

Effect of Multisensory Training on Gait Variability in People With Parkinson's Disease

People with Parkinson's disease (PD) were characterized by many motor symptoms, including rigidity, postural instability, bradykinesia, and resting tremor. These motor symptoms might cause gait dysfunction. Gait dysfunction represented a common sign of PD, including reduced gait velocity, reduced stride length, reduced arm swing, and increased gait variability. Poor postural control in people with PD might result to increase gait variability and then increase fall risk. Previous studies reported that proprioceptive-vestibular multisensory training improved postural stability in people with PD. However, no literature investigated the effects of proprioceptive-vestibular multisensory training on gait variability. Therefore, the purpose of this study is to examine the effect of proprioceptive-vestibular multisensory training on gait variability in people with PD.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Idiopathic PD
  • Hoehn and Yahr stage I to III
  • Age 60~80 y/o
  • Mini-Mental State Examination (MMSE) ≥24
  • Ability to ambulate independently (with or without walking aid)

Exclusion Criteria:

  • Affecting the peripheral vestibular system
  • Medical condition that substantially influenced their gait and balance performance
  • People had joined any rehabilitation past 1 month

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Multisensory training group
The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks
Other: Multisensory training
Multisensory training included marching on the foam with visual deprivation and treadmill training with visual deprivation
Active Comparator: Conventional training group.
The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks
Other: Conventional training
Conventional training included strengthening, balance training and gait training

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Gait variability
Time Frame: Change from baseline at 6 weeks
Using GAITRite system to measure coefficient of variation
Change from baseline at 6 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Gait performance
Time Frame: Change from baseline at 6 weeks
Using the GAITRite system to evaluate saptiotemporal parameters
Change from baseline at 6 weeks
Sensory organization test
Time Frame: Change from baseline at 6 weeks
Using NeuroCom Smart Balance Master
Change from baseline at 6 weeks
Timed up and go test
Time Frame: Change from baseline at 6 weeks
To evaluate functional mobility
Change from baseline at 6 weeks
Dynamic Gait Index
Time Frame: Change from baseline at 6 weeks
To evaluate functional mobility
Change from baseline at 6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Yang Ming University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Anticipated)

September 1, 2021

Primary Completion (Anticipated)

December 31, 2022

Study Completion (Anticipated)

December 31, 2022

Study Registration Dates

First Submitted

August 21, 2021

First Submitted That Met QC Criteria

August 26, 2021

First Posted (Actual)

August 30, 2021

Study Record Updates

Last Update Posted (Actual)

August 30, 2021

Last Update Submitted That Met QC Criteria

August 26, 2021

Last Verified

August 1, 2021

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 21MMHIS153e

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Parkinson Disease

Clinical Trials on Multisensory training

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in United Kingdom

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe