Does Extraction Difficulty of Mandibular Impacted Third Molars Mirror Post-op Outcomes?

The tooth of the patient who applies to the clinic for the impacted wisdom tooth will be classified according to Escoda's difficulty classification. Before the extraction, patients' interincisal, tragus-commissural, and lateral canthus-angulus distances, Oral Health Impact Profile -14 (OHIP-14) scores, and serum levels of CRP and D-Dimer will be measured.

Operation time will be recorded. After the operation, on 4th-day patients' patients' interincisal, tragus-commissural, and lateral canthus-angulus distances, Oral Health Impact Profile -14 (OHIP-14) scores, and serum levels of CRP and D-Dimer and Visual Analogue Scale (for pain) scores will be measured and recorded. On the 10th day, all these measurements will be repeated.

All recorded data will be evaluated for possible correlations based on extraction difficulties.

Study Overview

• Status: Completed
• Conditions: Impacted Third Molar Tooth
• Intervention / Treatment: Procedure: Extraction of impacted mandibular third molar

• Study Type: Interventional
• Enrollment (Actual): 66
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Konya
    • Selçuklu, Konya, Turkey, 42250
      • Selcuk University, Dentistry Faculty

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 40 years (Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Having extraction of only the mandibular third molar
• No systemic disease
• Signing an informed consent
• No dental phobia or anxiety
• No lesion around the impacted tooth
• Presence of adjacent second molar

Exclusion Criteria:

• Infection after surgery
• Alveolar osteitis
• Not to participate in any follow-up control appointments

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Low Difficulty; Classified as low difficulty according to Escoda's classification	Procedure: Extraction of impacted mandibular third molar; surgical extraction of impacted mandibular third molar tooth
Experimental: Modarate Difficulty; Classified as modarate difficulty according to Escoda's classification	Procedure: Extraction of impacted mandibular third molar; surgical extraction of impacted mandibular third molar tooth
Experimental: High Difficulty; Classified as high difficulty according to Escoda's classification	Procedure: Extraction of impacted mandibular third molar; surgical extraction of impacted mandibular third molar tooth

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Operation time	Duration of surgical intervention	after the operation
interincisal distance change	The distance between the right upper central incisor incisal line and the right upper incisor incisal line will be measured before the surgery, on the 5th and 10th day. The changes will be evaluated.	before the surgery, 4th and 10th days
tragus-commissura distance	the distance between tragus and angulus in relevant side will be measured before the surgery, on the 5th and 10th day. The changes will be evaluated.	before the surgery, 4th and 10th days
lateral canthus-angulus distance	the distance between lateral canthus and angulus in relevant side will be measured before the surgery, on the 5th and 10th day. The changes will be evaluated.	before the surgery, 4th and 10th days
OHIP-14 score	Oral Health Impact Profile Score(14-70; higher is worse)	before the surgery, 4th and 10th days
VAS score	Visual analog scale score(0-10; higher is worse)	4th and 10th days
CRP serum level	Serum levels of CRP will be measured via blood samples before the surgery and the 5th day.	before the surgery and 4th day
D-Dimer serum level	Serum levels of D-Dimer will be measured via blood samples before the surgery and the 5th day.	before the surgery and 4th day

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
interincisal distance	the distance between right upper central incisor incisal line and right upper incisor incisal line	3rd and 10th day
tragus-commissura distance	the distance between tragus and angulus in relevant side	3rd and 10th day
lateral canthus-angulus distance	the distance between lateral canthus and angulus in relevant side	3rd and 10th day
VAS score	Visual analog scale score(0-10; higher is worse)	10th day
OHIP -14 score	Oral Health Impact Profile Score(14-70; higher is worse)	3rd, 10th and 30th day

Collaborators and Investigators

• Sponsor: Selcuk University
• Investigators: Study Chair: Gökhan Gürses, Selcuk Universty/Dentistry Faculty; Principal Investigator: Mert Doğrul, Selcuk Universty/Dentistry Faculty

Study record dates

Study Major Dates

• Study Start (Actual): April 9, 2024
• Primary Completion (Actual): May 5, 2025
• Study Completion (Actual): May 12, 2025

Study Registration Dates

• First Submitted: September 10, 2021
• First Submitted That Met QC Criteria: September 10, 2021
• First Posted (Actual): September 20, 2021

Study Record Updates

• Last Update Posted (Actual): May 15, 2025
• Last Update Submitted That Met QC Criteria: May 12, 2025
• Last Verified: May 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Tooth, Impacted
• Other Study ID Numbers: SelcukU01

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No