Intubation Prediction in COVID-19 Patients Treated With Awake Prone Positioning (Intub_prone)

June 2, 2022 updated by: Piquilloud Imboden Lise, University of Lausanne Hospitals

Intubation Prediction in Sars-CoV-2 Patients Treated With Awake Prone Positioning

Retrospective study in Sars-Cov 2 patients hospitalised in ICU. We aim to explore the effects of Awake prone positioning on oxygenation and intubation rate.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

42

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Switzerland
    • Vaud
      • Lausanne, Vaud, Switzerland, 1011
        • Lausanne University Hospitals

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Sars-CoV-2 pneumonia patients with severe hypoxemia

Description

Inclusion Criteria:

  • Sars-CoV-2 pneumonia
  • ICU stay
  • Severe hypoxemia but non intubated

Exclusion Criteria:

  • Intubated before admission
  • Denied consent for data analysis
  • Do not intubate order at ICU admission

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Intubation rate
Time Frame: Once between ICU admission and extubation
Once between ICU admission and extubation

Secondary Outcome Measures

Outcome Measure
Time Frame
Alveolo-arterial gradient change
Time Frame: Within 6 hours before and 6 hours after each pronation
Within 6 hours before and 6 hours after each pronation
Blood gas analysis
Time Frame: Within 6 hours before and 6 hours after each pronation
Within 6 hours before and 6 hours after each pronation
Respiratory pattern
Time Frame: Within 6 hours before and 6 hours after each pronation
Within 6 hours before and 6 hours after each pronation
Mortality
Time Frame: Up to 28 days from ICU admission
Up to 28 days from ICU admission

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Lausanne Hospitals

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 16, 2021

Primary Completion (Actual)

April 30, 2022

Study Completion (Actual)

April 30, 2022

Study Registration Dates

First Submitted

September 16, 2021

First Submitted That Met QC Criteria

September 27, 2021

First Posted (Actual)

September 29, 2021

Study Record Updates

Last Update Posted (Actual)

June 3, 2022

Last Update Submitted That Met QC Criteria

June 2, 2022

Last Verified

September 1, 2021

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Intub_prone

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Acute Hypoxemic Respiratory Failure

Clinical Trials on Awake prone positioning

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe