- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05491928
Treatment of Metastatic Cancer in Terminally Diagnosed Patients
August 31, 2022 updated by: Matrix Biomed, Inc.
The objective is to provide terminally diagnosed patients with a last line of treatment while improving overall quality of life.
Tempol can be added to any chemotherapy regimen to potentially reduce side effects and overcome chemoresistance.
Study Overview
Detailed Description
The objective is to provide terminally diagnosed patients assigned to palliative care and palliative chemotherapy a last line treatment with Tempol.
In vivo studies have shown Tempol to work synergistically with a number of chemotherapy agents increasing treatment response and reducing chemoresistance.
Additionally, Tempol has been shown to provide protection to non-cancerous cells allowing for increased chemotherapy dosing by reducing side effects.
Tempol inhibits HIF-1/VEGF among others in cancerous cells while upregulating GSH/NrF2 among others in non-cancerous cells.
Study Type
Expanded Access
Expanded Access Type
- Individual Patients
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Colorado
-
Aurora, Colorado, United States, 80045
- Available
- UCHealth University of Colorado Cancer Center - Anschutz Medical Campus
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
All
Description
Inclusion Criteria:
- metastatic terminally diagnosed cancer
Exclusion Criteria:
-
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
July 30, 2022
First Submitted That Met QC Criteria
August 4, 2022
First Posted (Actual)
August 8, 2022
Study Record Updates
Last Update Posted (Actual)
September 1, 2022
Last Update Submitted That Met QC Criteria
August 31, 2022
Last Verified
August 1, 2022
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- MBI-23-01
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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Clinical Trials on Tempol
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Matrix Biomed, Inc.MedStar GeorgetownNot yet recruitingGlioblastoma | Glioblastoma MultiformeUnited States
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Mitos PharmaceuticalsUnknown
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Adamis Pharmaceuticals CorporationTerminated
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Lipocine Inc.Completed
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The University of Texas at ArlingtonCompletedCardiovascular Diseases | Cardiovascular Risk Factor | VasoconstrictionUnited States
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Matrix Biomed, Inc.RecruitingMucositis | Nephrotoxicity | OtotoxicityUnited States
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The University of Texas at ArlingtonCompletedCardiovascular Diseases | Vasodilation | Cardiovascular Risk FactorUnited States