Gastric Volume After Drinking 175 ml of Ice Water Prior to Gastroscopy in Healthy Adult Patients

Gastric Emptying and Gastric Volume After Ingestion of 175 ml of Ice Water Prior to Elective Gastroscopy in Healthy Adults

Recommendation for fluid fasting is two hours prior to anaesthesia, however, less may be acceptable. The current study compares ingestion of 175 ml ice water prior to elective gastroscopy vs. standard fasting on gastric residual volume.

Study Overview

• Status: Completed
• Conditions: Fasting; Perioperative Pulmonary Aspiration
• Intervention / Treatment: Other: Ice water

Detailed Description

Recommendations regarding fasting requirements prior to general anaesthesia is two hours for fluids. Recent research indicates that reduced fluid fasting time may be acceptable. The current study aimed to compare ingestion of 175 ml ice water 15 minutes prior to procedure compared to standardized fasting regimen on residual gastric volumes in patients receiving elective gastroscopy, as these volumes may have implications for fasting requirements.

• Study Type: Interventional
• Enrollment (Actual): 50
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Denmark
  • North Denmark
    • Hjørring, North Denmark, Denmark, 9800
      • Department of Anaestesia

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Scheduled for elective gastroscopy in a medical outpatient clinic
• American Society of Anesthesiologists physical status classification system category (ASA score) I or II
• Age 18 years or above

Exclusion Criteria:

• Any increased risk of aspiration, eg. dysphagia, previous aspiration, non-fasting status, or known alcohol abuse
• Suspected delayed gastric emptying, eg. regular opioid use within three days
• Enteral pre-medication required
• Any structural gastric or esophageal diseases

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: 175 ml ice water; Ingestion of 175 ml ice water 15 minutes prior to gastroscopy	Other: Ice water; Ingestion of 175 ml iced tap water 15 minutes prior to elective gastroscopy; Other Names: Iced tap water
No Intervention: Fasting; Continued fasting

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Gastric residual volume	Aspired residual gastric fluid volume at start of gastroscopy	15 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Nausea and dyspepsia	Proportion of patients reporting nausea or dyspeptic symptoms prior to gastroscopy	15 minutes

Collaborators and Investigators

• Sponsor: Vendsyssel Hospital
• Investigators: Study Chair: Kjeld Damgaard, MD, PhD, Regional Hospital of Northern Denmark, Hjørring

Study record dates

Study Major Dates

• Study Start (Actual): March 3, 2020
• Primary Completion (Actual): June 17, 2021
• Study Completion (Actual): June 17, 2021

Study Registration Dates

• First Submitted: January 5, 2023
• First Submitted That Met QC Criteria: January 5, 2023
• First Posted (Estimate): January 16, 2023

Study Record Updates

• Last Update Posted (Estimate): January 16, 2023
• Last Update Submitted That Met QC Criteria: January 5, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Keywords: Anaesthesia; Gastroscopy; Gastric volume
• Other Study ID Numbers: N-20190056

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No