- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05727826
The Investigation of the Effectiveness of Vibratory Stimulation on Upper Limb Function, Pain and Sensation in Patients With Stroke.
Study Overview
Detailed Description
One of the major disadvantages is the loss of muscle strength in patients with post-stroke hemiplegia. Muscle weakness is caused after a stroke, followed by limited movement . Tactile and proprioceptive sensations are reduced in up to 65% of hemiplegic patients. Furthermore, pain, temperature, and touch are reduced. Because the ability to perceive these sensory features is impaired, recognizing objects by touch or exploring the environment can be difficult. Furthermore, it is stated that the senses are important and influence the recognition of skilled movements. A disorder has negative consequences for safety, natural hand use, the ability to maintain an appropriate level of strength while grasping without vision, and difficulties with object management. In this way, regaining motor control is a complex and time-consuming process. The increased unmasking of neural covert connections and the number of synapses in dendrites are two mechanisms by which the brain reorganizes itself. It has been observed that functionally relevant adaptive changes occur in the brain following an injury .Segmental muscle vibration (SMV) is a technique that uses a mechanical apparatus to deliver a vibratory stimulus to a specific tendon. As a result of the facilitation of muscle spindle primary ends, SMV provides Ia inputs. By managing intracortical inhibition and activating sensory inputs to the primary motor cortex, Ia sensory inputs facilitated by SMV can alter the activation of the corticospinal pathway. Transcranial magnetic simulation was used in a previous study after low-amplitude SMV was applied to the flexor carpi radialis muscle and inner hand muscles, and increased excitability in the primary motor cortex .While systematic data on improving human somatosensation are lacking, many accounts indicate that there is room for improvement. Furthermore, previous research on lesioned primates has shown that extensive training in touch, proprioception, and vibration improves even the most complex discriminating abilities. It also aided in the identification of the somatosensory cortex. As a result, the purpose of this study was to better understand the pure effect of repeated vibratory stimulation and its long-term effects two weeks after the last intervention session, when compared to the experimental or control groups.
In summary, studies in the literature have used a vibratory stimulation device to perform arm and wrist flexor motion therapy. This will be the first study to look at how vibratory stimulation of the forearm and arm extensor muscles affects upper extremity function, sensation, and pain parameters in hemiplegic patients.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Hager E Yahya, Mcs
- Phone Number: 5527913211
- Email: hageryahya13@gmail.com
Study Locations
-
-
Ataşahir
-
Istanbul, Ataşahir, Turkey, 34755
- Recruiting
- Yeditepe University
-
Contact:
- Elif T Çil, Phd
- Phone Number: 02165780000
- Email: elif.cil@yeditepe.edu.tr
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- ADULT
- OLDER_ADULT
- CHILD
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion criteria:
- no complaints of pain caused by induced vibration
- >24 points in Mini Mental State Examination
- Having a diagnosis of hemiplegia
Exclusion criteria:
• Other neurological problems, Parkinson's
Study Plan
How is the study designed?
Design Details
- Primary Purpose: OTHER
- Allocation: NA
- Interventional Model: SEQUENTIAL
- Masking: NONE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: stroke patients
individuals with hemiplegia after Hemorrhagic or Infarction stroke
|
The experimental group received a 60 Hz vibration stimulation treatment using the SMV method three times per week for two weeks (EG).
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Box and block test (BBT)
Time Frame: 60 seconds
|
Box and block test (BBT) which is used to assess unilateral gross manual dexterity and functional abilities of upper extremity specifically for hand and wrist functionality.
A simple, quick, and inexpensive test, it takes only a few minutes to complete.
In the BBT, a wooden box is divided into two compartments by a partition, and 150 blocks are placed inside.
During BBT administration, the patient is position at the table and asked to move as many blocks as possible in 60 seconds between two individual compartments which are equal in size.
A client's score is determined by the number of blocks transferred between compartments within 60 seconds.
The scores for each hand should be kept separately.
Better manual dexterity is reflected in higher scores.
When the BBT is being conducted, the evaluator should be aware of whether the client's fingertips cross the partition.
In order to count blocks, this condition must be met.
|
60 seconds
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Visual Analogue Scale (VAS)
Time Frame: 2 minutes
|
Visual Analogue Scale (VAS) is used to measure the severity of pain in patients, it can also be useful at recording patients' pain progression, or compare pain severity between individuals with similar conditions.
|
2 minutes
|
Other Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
monofilament test
Time Frame: 5 minutes
|
In the evaluation of light touch and pressure protective senses, monofilament is used to test sensory levels and detect diminishing and returning senses.
This evaluation should be carried out in a very systematic manner.
The therapist begins with the smallest monofilament and progresses to the largest filament in the correct order, but the test is stopped and the value is recorded when the patient detects the smallest monofilament being tested.
It is applied to the anterior and posterior surfaces of the fingers from the first to the fifth, distal to proximal.
This evaluation tool is made up of a series of monofilaments that vary in thickness and diameter.
These monofilaments have gradient strengths ranging from 0.086 gm to 448 gm.
These monofilaments are used to assess sensory impairment.
|
5 minutes
|
Collaborators and Investigators
Sponsor
Publications and helpful links
Helpful Links
Study record dates
Study Major Dates
Study Start (ANTICIPATED)
Primary Completion (ANTICIPATED)
Study Completion (ANTICIPATED)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (ESTIMATE)
Study Record Updates
Last Update Posted (ESTIMATE)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- SMV on stroke patient
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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