- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06036251
COVID-19 Pandemic Induced Stress and Symptoms
September 22, 2023 updated by: University of California, San Francisco
COVID-19 Pandemic Induced Stress and Symptoms - Follow-up Study
The previous survey of oncology patients at University of California, San Francisco in 2020-2021 found an alarmingly high symptom burden and high levels of stress and loneliness among respondents.
This is a follow-up study with the same sample of oncology patients and survivors who participated in the previous study
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
OBJECTIVES:
- Evaluate for associations among general and disease-specific measures of stress and measures of social isolation and loneliness.
- Evaluate for associations between general and disease-specific stress and common symptoms associated with cancer and its treatments.
- Evaluate for associations between social isolation and loneliness and common symptoms associated with cancer and its treatments.
- Evaluate for associations between social isolation and loneliness and health behaviors and quality of life (QOL) as compared to our last survey. as a baseline.
- Evaluate for changes in stress, social isolation, loneliness and symptom burden between the two time points.
OUTLINE:
Patients will be asked to complete self-report questionnaires online. Questionnaires will take approximately 60 minutes to complete. and directed to take rest periods at 20 minute intervals. Participants will be given two weeks to complete the instruments.
Study Type
Observational
Enrollment (Actual)
415
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
California
-
San Francisco, California, United States, 94143
- University of California, San Francisco
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Sampling Method
Probability Sample
Study Population
Only previous patients and survivors who took part in our last COVID survey in 2020-2021 who agreed to be re-contacted for future research at University of California, San Francisco
Description
Inclusion Criteria:
- Current/Previous diagnosis of cancer
- Able to read, write, and understand English
- Able to complete the study questionnaires on line
- Able consent to participate.
Exclusion Criteria:
- Participants of our previous COVID survey study who opted out of future research.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Prior oncology participants
Oncology patients at University of California, San Francisco who participated in the previous study which evaluated the additional stressors imposed by COVID-19 (i.e., social isolation, loneliness) and ongoing general and disease specific stress on the symptom burden of cancer patients and survivors.
|
Self-reported quality of life (QOL) measures completed online
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Correlation of scores on perceived stress scale (PSS) and social isolation scale (SIS)
Time Frame: 2 days
|
Scores on the Perceived Stress Scale (PSS) from the previous study and this study, along with scores on the Social Isolation Scale (SIS) from the previous study, this study will be compared.
The PSS is a 10-item questionnaire which asks participants about feelings and thoughts during the last month.
Scores of each item ranging from 0 = "Never" to 4 = "Very Often" for a total score range of 0 to 40.
Scores are obtained by reversing responses (e.g., 0 = 4, 1 = 3, 2 = 2, 3 = 1 & 4 = 0) to 4 of the 10 positively stated items and scores are calculated by summing the total.
Higher scores indicate higher degree of perceived stress.
The Social Isolation Scale (SIS) is a measure used to assess an individual's tendency to isolate themselves from social situations.
Scores on this scale are distributed with a mean of 15.0 and a standard deviation of 4.5.
|
2 days
|
Correlation of scores on the perceived stress scale (PSS) and loneliness scale
Time Frame: 2 days
|
Scores on the Perceived Stress Scale (PSS) from the previous study and this study, along with scores on the University of California, Los Angeles (UCLA) Loneliness Scale from the previous study, and this study will be compared.
The PSS is a 10-item questionnaire which asks participants about feelings and thoughts during the last month.
Scores of each item ranging from 0 = "Never" to 4 = "Very Often" for a total score range of 0 to 40.
Scores are obtained by reversing responses (e.g., 0 = 4, 1 = 3, 2 = 2, 3 = 1 & 4 = 0) to 4 of the 10 positively stated items and scores are calculated by summing the total.
Higher scores indicate higher degree of perceived stress.
The 3-item UCLA loneliness scale is a 3-item scale used for measuring loneliness with scores ranging from 1='Hardly ever" to 3=Often.
Scores are summed to generate a total score with higher scores indicating a higher degree of loneliness.
|
2 days
|
Correlation of scores on the perceived stress scale (PSS) and symptom severity scores
Time Frame: 2 days
|
Scores on the PSS from the previous study and this study, along with scores on Memorial Symptom Assessment Scale (MSAS) from the previous study, and this study will be compared.
The PSS is a 10-item questionnaire which asks participants about feelings and thoughts during the last month.
Scores of each item ranging from 0 = "Never" to 4 = "Very Often" for a total score range of 0 to 40.
Scores are obtained by reversing responses (e.g., 0 = 4, 1 = 3, 2 = 2, 3 = 1 & 4 = 0) to 4 of the 10 positively stated items and scores are calculated by summing the total.
Higher scores indicate higher degree of perceived stress.
The MSAS is used to assess common physical symptoms experienced by persons with cancer.
The values for severity and frequency measurements are 1='slight' or 'rarely' and 4= 'very severe'/'almost constantly' .Higher values indicate a greater number of symptoms.
|
2 days
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Christine Miaskowski, RN,PhD,FAAN, University of California, San Francisco
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Miaskowski C, Paul SM, Snowberg K, Abbott M, Borno HT, Chang SM, Chen LM, Cohen B, Cooper BA, Hammer MJ, Kenfield SA, Kober KM, Laffan A, Levine JD, Pozzar R, Rhoads K, Tsai KK, Van Blarigan EL, Van Loon K. Loneliness and symptom burden in oncology patients during the COVID-19 pandemic. Cancer. 2021 Sep 1;127(17):3246-3253. doi: 10.1002/cncr.33603. Epub 2021 Apr 27.
- Miaskowski C, Paul SM, Snowberg K, Abbott M, Borno H, Chang S, Chen LM, Cohen B, Hammer MJ, Kenfield SA, Kober KM, Levine JD, Pozzar R, Rhoads KF, Van Blarigan EL, Van Loon K. Stress and Symptom Burden in Oncology Patients During the COVID-19 Pandemic. J Pain Symptom Manage. 2020 Nov;60(5):e25-e34. doi: 10.1016/j.jpainsymman.2020.08.037. Epub 2020 Sep 2.
- Miaskowski C, Paul SM, Snowberg K, Abbott M, Borno H, Chang S, Chen LM, Cohen B, Cooper BA, Hammer MJ, Kenfield SA, Laffan A, Levine JD, Pozzar R, Tsai KK, Van Blarigan EL, Van Loon K. Oncology patients' perceptions of and experiences with COVID-19. Support Care Cancer. 2021 Apr;29(4):1941-1950. doi: 10.1007/s00520-020-05684-7. Epub 2020 Aug 18.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
February 1, 2023
Primary Completion (Actual)
April 30, 2023
Study Completion (Actual)
April 30, 2023
Study Registration Dates
First Submitted
September 6, 2023
First Submitted That Met QC Criteria
September 6, 2023
First Posted (Actual)
September 13, 2023
Study Record Updates
Last Update Posted (Actual)
September 26, 2023
Last Update Submitted That Met QC Criteria
September 22, 2023
Last Verified
September 1, 2023
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 23804
- NCI-2023-06245 (Registry Identifier: NCI Clinical Trials Reporting Program (CTRP))
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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