Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.

December 26, 2023 updated by: Riphah International University

Combined Effects of Neural Mobilization With Task Based Activities on Spasticity and Motor Function of Upper Limb in Patients With Chronic Stroke.

Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb dysfunction. In this study we use two techniques to improve upper limb motor dysfunction and reduce spasticity. One is task-based activities which is used to improve motor function and focus on active participation rather than normal movement pattern and other is neural mobilization which aims to reduce spasticity which is most common in stroke patients.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

This study will be randomized controlled trial. Participants having stroke past 6 month to 1 year and mini mental state examination score >21 will be included in this study. And participants with severe orthopedic deformity, joint pain and visual impairment will be excluded from this study. The sample size will consist of 34 participants selected through non probability convenient sampling technique, which will further be randomized through sealed envelope method and will divide into two groups .Data will be collected using assessment tools, including the Fugl Mayer assessment scale, box and block test and wolf motor function test. 17 Participants will be assigned to the interventional group (A )which will undergo neural mobilization of median nerve with task based activities .Neural mobilization technique will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 week.

while task based activities will be performed with the dosage of 45 minutes session 5 days weekly for 6 weeks and 17 participants will be assigned to control group (B

)which will undergo only neural mobilization of median nerve and will receive neural mobilization with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 weeks. After applying both interventions motor function improvement and spasticity reduction will be measured by using BBT, wolf motor scale and fugl -Meyer assessment scale and data will be analyzed through sPss Version 25.

Study Type

Interventional

Enrollment (Estimated)

34

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Pakistan
    • Punjab
      • Lahore, Punjab, Pakistan, 5433
        • Recruiting
        • Ripha International University
        • Contact:
        • Contact:
        • Principal Investigator:
          • Asrar Yousaf
        • Sub-Investigator:
          • Tehreem Fatima

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Male and female stroke patients.
  • 6 month to one year post stroke .
  • Age 30-55
  • Stable patients
  • Mini - mental state examination>2
  • Modified ashworth Scale equal<+1

Exclusion Criteria:

  • Orthopedic deformity
  • Patients undergo bottulinuminjection toxin injection
  • Visual impairments
  • Joint pain (elbow, shoulder, wrist)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Neural mobilization
Neural mobilization technique will be perormed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for Six week.
Other: Neural mobilization
Neural mobilization will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval of rest between each set for 4 days weekly for six week
Other Names:
  • Task based activities
Experimental: Task based activities
Task based activities consisted of different type of task which will be performed with the doasage of 45 minutes per session 5 days weekly for 6 weeks.
Other: Task based activities
Task based activities consisted of different types task which will be performed with the dosage of 45 minute session 5 days weekly for six week.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Box and block test
Time Frame: 6 weeks
It measures unilateral gross manual dexterity
6 weeks
Fugl -Meyer assessment scale
Time Frame: 6 weeks
It measure motor ability of upper extremity
6 weeks
Wolf motor Function Test
Time Frame: 6 weeks
The Wolf Motor Function Test (WMFT) quantifies upper extremity (UE) motor ability through timed and functional tasks
6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Memona Ayesha, Ms-NMPT, Ripha International University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 17, 2023

Primary Completion (Estimated)

January 15, 2024

Study Completion (Estimated)

January 22, 2024

Study Registration Dates

First Submitted

November 9, 2023

First Submitted That Met QC Criteria

November 9, 2023

First Posted (Actual)

November 14, 2023

Study Record Updates

Last Update Posted (Actual)

December 29, 2023

Last Update Submitted That Met QC Criteria

December 26, 2023

Last Verified

December 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/RCR &/23/0233

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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