Effect of Dexamethasone Adjuvant in Combined Supraclavicular Block and Suprascapular Block Versus Interscalene Block in Patients Undergoing Shoulder Arthroscopy

In this study the investigators aim to compare the effect of the suprascapular- supraclavicular nerve block in association with dexamethasone to that of the interscalene brachial plexus block on analgesic effect during arthroscopic shoulder surgery, as postoperative pain scores ,postoperative consumption of analgesic rescue medications and diaphragmatic excursion assessment.

Study Overview

• Status: Recruiting
• Conditions: Dexamethasone; Shoulder Arthroscopy Blocks
• Intervention / Treatment: Procedure: Shoulder arthroscopy blocks

• Study Type: Interventional
• Enrollment (Estimated): 60
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Mohamed Ahmed; Phone Number: 01151994269; Email: mohamedelkhatib90@gmail.com
• Study Contact Backup: Name: Mohamed Talaat; Phone Number: +20 106 201 2031

Study Locations

• Egypt
  • Assiut, Egypt
    • Recruiting
    • Assiut University
    • Contact: Assiut University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• ASA status 1,2.

  • Age 18 years or older
  • Elective shoulder arthroscopic surgery under general anesthesia and nerve block performed preoperatively.

Exclusion Criteria:

• • Patient refusal

  • Serious cardiac arrhythmias (including atrial fibrillation) or unstable coronary artery disease.
  • Use of drugs that act on the autonomic nervous system (including β- blockers).
  • Coagulation disorders..
  • Anatomical disorders and/or neuropathic disease.
  • BMI above 40.
  • History of substance abuse.
  • Chronic use of psychotropic and/or opioid.
  • History of psychiatric diseases needing treatment.
  • Allergy to any drug in the study protocol.
  • Failure of nerve block performed in the preoperative block room when tested prior to entering the operating room (i.e. lack of loss of sensation to ice at the shoulder incision level).

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Interscalene block in shoulder arthroscopy	Procedure: Shoulder arthroscopy blocks; Effect of dexamethasone adjuvant in combined supraclavicular block and suprascapular block versus Interscalene block in patients undergoing shoulder arthroscopy.
Active Comparator: Combined Supraclavicular block and suprascapular block in shoulder arthroscopy	Procedure: Shoulder arthroscopy blocks; Effect of dexamethasone adjuvant in combined supraclavicular block and suprascapular block versus Interscalene block in patients undergoing shoulder arthroscopy.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Postoperative analgesia by visual analog scale (VAS).	The primary outcome of this study will be to evaluate and compare between suprascapular-supraclavicular nerve block in association with dexamethasone to that of the interscalene brachial plexus block on postoperative analgesia by vas score during 48h postoperatively ( 2h , 6h , 12h, 24h and 48h). The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be').	48 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Diaphragmatic excursion	Assessment of diaphragmatic excursion by ultrasound preoperatively and 1hour postoperatively	1hour postoperatively

Collaborators and Investigators

• Sponsor: Assiut University

Study record dates

Study Major Dates

• Study Start (Actual): February 25, 2024
• Primary Completion (Estimated): December 1, 2025
• Study Completion (Estimated): January 1, 2026

Study Registration Dates

• First Submitted: December 26, 2023
• First Submitted That Met QC Criteria: February 15, 2024
• First Posted (Actual): February 16, 2024

Study Record Updates

• Last Update Posted (Actual): April 22, 2025
• Last Update Submitted That Met QC Criteria: April 17, 2025
• Last Verified: February 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: Shoulder nerve blocks

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No