Compare the Agility Exercise and Resistance Exercise on Physical Function and Stability in Osteoporotic Women

Tainan Hospital, Ministry of Health and Welfare, Taiwan

Osteoporosis weakens bones with age, increasing fracture risk. Exercise improves physical function and reduces falls, crucial for preventing osteoporotic fractures, especially with balance, resistance, and multi-component training. Agility exercise, integrating various aspects like aerobic, strength, balance, and cognitive tasks, is promising for fall prevention in older adults, though its effectiveness in osteoporosis is not extensively studied.

This study compares agility and resistance exercise impacts on physical function and balance stability in postmenopausal osteoporosis. Fifty-one women (average age: 68±6.3y, BMI: 22.3±2.7 kg/m2) were divided into agility exercise (AG), resistance exercise (RG), and control groups (CG) through purposive sampling. AG and RG received added intervention training once a week for 2 hours over 12 weeks. Main outcomes included physical function and balance stability measured through various tests.

Study Overview

• Status: Completed
• Conditions: Physical Function; Postmenopausal Osteoporosis; Fall Prevention; Agility Exercise; Balance Stability
• Intervention / Treatment: Biological: Physical training of agility; Biological: Physical training of resistance

Detailed Description

Main activities of agility training group (AG): Use rope ladders and cones to perform multiple tasks of direction changes, acceleration and deceleration of footsteps, hand and foot coordination and spatial orientation training.

Main activities of resistance training group (AG): Resistance training for upper and lower limb muscles and core muscles, including squats, use of elastic bands, and simple bars.

• Study Type: Interventional
• Enrollment (Actual): 51
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Taiwan
  • Tainan, Taiwan
    • Chen, Ying-Chen

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• women with osteoporosis( diagnosed with DXA, T-score≦-2.5 in L-spine or hip)
• postmenopausal, more than 50 years old,

Exclusion Criteria:

• unable to attend the training sessions due to physical problems
• had joined previous exercise program

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Agility exercise training.; Participants attend training class focused on agility training. Rope ladders and cones are used to perform multiple tasks of direction changes, acceleration and deceleration of footsteps, hand and foot coordination and spatial orientation training.	Biological: Physical training of agility; A grouped training for older adults in the community. The training classed lasted for 12 weeks, one session a week for 120 mins, and are under instructed by a trained experienced sport instructor. Use rope ladders and cones to perform multiple tasks of direction changes, acceleration and deceleration of footsteps, hand and foot coordination and spatial orientation training,
Active Comparator: Resistance exercise training.; Participants attend training class focused on resistance training. Resistance training for upper and lower limb muscles and core muscles, including squats, use of elastic bands, and simple bars.	Biological: Physical training of resistance; A grouped training for older adults in the community. The training classed lasted for 12 weeks, one session a week for 120 mins, and are under instructed by a trained experienced sport instructor. Resistance training for upper and lower limb muscles and core muscles, including squats, use of elastic bands, and simple bars
No Intervention: Control; Participants only receive osteoporosis education usual care.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Physical function of upper limb strength	arm curl in 30 secs	after the completed training course, about 12 weeks
Physical function of upper limbs strength	Hand grip	after the completed training course, about 12 weeks
Physical function of lower limbs	Walking speed	after the completed training course, about 12 weeks
Physical function of dynamic balance	Up and go test	after the completed training course, about 12 weeks
Physical function of lower limbs	Sit to stand in 30 secs	after the completed training course, about 12 weeks
Physical function of static balance	One leg stand test	after the completed training course, about 12 weeks
Stability index	Biodex balance system device	after the completed training course, about 12 weeks

Collaborators and Investigators

• Sponsor: Tainan Hospital, Ministry of Health and Welfare

Publications and helpful links

General Publications

• Donath L, van Dieen J, Faude O. Exercise-Based Fall Prevention in the Elderly: What About Agility? Sports Med. 2016 Feb;46(2):143-9. doi: 10.1007/s40279-015-0389-5.
• Lichtenstein E, Morat M, Roth R, Donath L, Faude O. Agility-based exercise training compared to traditional strength and balance training in older adults: a pilot randomized trial. PeerJ. 2020 Apr 14;8:e8781. doi: 10.7717/peerj.8781. eCollection 2020.
• Morat M, Morat T, Zijlstra W, Donath L. Effects of multimodal agility-like exercise training compared to inactive controls and alternative training on physical performance in older adults: a systematic review and meta-analysis. Eur Rev Aging Phys Act. 2021 Feb 25;18(1):4. doi: 10.1186/s11556-021-00256-y.
• Miko I, Szerb I, Szerb A, Bender T, Poor G. Effect of a balance-training programme on postural balance, aerobic capacity and frequency of falls in women with osteoporosis: A randomized controlled trial. J Rehabil Med. 2018 Jun 15;50(6):542-547. doi: 10.2340/16501977-2349.

Study record dates

Study Major Dates

• Study Start (Actual): July 14, 2021
• Primary Completion (Actual): May 31, 2022
• Study Completion (Actual): December 31, 2022

Study Registration Dates

• First Submitted: April 6, 2024
• First Submitted That Met QC Criteria: June 8, 2024
• First Posted (Actual): June 13, 2024

Study Record Updates

• Last Update Posted (Actual): August 20, 2024
• Last Update Submitted That Met QC Criteria: August 19, 2024
• Last Verified: August 1, 2024

More Information

Terms related to this study

• Keywords: physical function; fall prevention; postmenopausal osteoporosis; agility exercise; multi-component exercise
• Additional Relevant MeSH Terms: Metabolic Diseases; Musculoskeletal Diseases; Bone Diseases; Bone Diseases, Metabolic; Osteoporosis; Osteoporosis, Postmenopausal
• Other Study ID Numbers: TainanHMHW

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No