The Effect of Refractive Errors on Central Corneal Thickness by Using Pentacam and IOL Master

June 26, 2024 updated by: Haidy Nayer Adly, Assiut University

The Effect of Refractive Errors on Central Corneal Thickness by Using Pentacam

To evaluate the impact of refractive errors on the central corneal thickness obtained by Pentacam and intraocular lenses (IOL) master in eyes with different refractive errors.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Central corneal thickness (CCT) is a key indicator of corneal health status and helps to assess corneal diseases. The normal corneal thickness is about 540 μm and mainly consists of the stroma, which is estimated at 450 μm in the center. The stroma provides vital structural integrity and plays a key role in helping maintain transparency. It has been reported, however, that CCT follows a diurnal pattern being 10 μm thicker in the morning due to reduced evaporation of water from underneath the closed eyelids

Study Type

Observational

Enrollment (Estimated)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

  1. Inclusion criteria:

    Subjects included in this study aged between20 and 41 asked for refractive surgery

  2. Exclusion criteria:-

    • Severe corneal scarrig or opacification., dystrophy
    • Patients with history of recent contact lens Ocular trauma.
    • Uveitis patients Patients with keratoconus.
    • Previous ocular or refractive surgey

Description

Inclusion Criteria:

  • Subjects included in this study aged between20 and 41 years, asked for refractive surgery

Exclusion Criteria:

  • patients with corneal scarrig or opacification.

    • Patients with corneal dystrophies.
    • Patients with keratoconus.
    • Previous ocular or refractive surgery.
    • Ocular trauma.
    • Uveitis patients.
    • Patients with history of recent contact lens wear.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Hypermetrope
Effect of hypermetropia on central corneal thickness by using pentacam and IOL master
Device: Pentacam and IOL master
Device used for measurement of central corneal thickness
Emmetrope
Effect of emmetropia on central corneal thickness by using pentacam and IOL master
Device: Pentacam and IOL master
Device used for measurement of central corneal thickness
Myopia
Effect of myopia on central corneal thickness by using pentacam and IOL master
Device: Pentacam and IOL master
Device used for measurement of central corneal thickness

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
To find if there a correlation between refractive errors and the central corneal thickness
Time Frame: Baseline
Study the effect of refractive errors on central corneal thickness
Baseline

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
To study if there a difference between measurement by pentacam and measurement of IOL master
Time Frame: Baseline
Study which device is more accurate in measuring the central corneal thickness and if there is any difference between the two devices
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Investigators

  • Study Director: Mahmoud Fathy rateb, Professor, Assiut University
  • Study Chair: Ahmed Abd el Nasser awad, Lecturer, Assiut University
  • Principal Investigator: Mohamed Tarek Abd el menaam, Professor, Assiut University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

July 15, 2024

Primary Completion (Estimated)

July 1, 2025

Study Completion (Estimated)

August 1, 2025

Study Registration Dates

First Submitted

June 26, 2024

First Submitted That Met QC Criteria

June 26, 2024

First Posted (Actual)

July 3, 2024

Study Record Updates

Last Update Posted (Actual)

July 3, 2024

Last Update Submitted That Met QC Criteria

June 26, 2024

Last Verified

June 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Central corneal thickness

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Central Corneal Thickness

Clinical Trials on Pentacam and IOL master

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Macedonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe