Correlation Analysis Between Corneal Biomechanics and Anterior Segment

October 28, 2023 updated by: Tianjin Eye Hospital

Correlation Analysis Between In-vivo Corneal Biomechanical Properties and Anterior Segment in Chinese Population

Evaluation of the ciliary muscle thickness, area, and anterior chamber angle, as well as anterior sclera thickness in subjects, to investigate the relationship between these measurements and corneal biomechanics. Clarify whether aqueous humor displacement, anterior sclera, and ciliary muscles influence the assessment of in vivo corneal biomechanics.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Tianjin
      • Tianjin, Tianjin, China
        • Tiajin Eye Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Patients premedicated for refractive surgery

Description

Inclusion Criteria:

  1. Best corrected visual acuity (BCVA) ≥ 20/20;
  2. No other eye diseases except myopia and astigmatism;
  3. The cornea was transparent, and there was no cloud or pannus;

Exclusion Criteria:

  1. Corneal disease;
  2. Ocular trauma;
  3. Previous ocular surgery;
  4. Any anterior segment diseases except cataract;
  5. Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination;
  6. Pregnant and lactating women;

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Normal group
Other: Pentacam, Corvis ST and Casia2
scleral and ciliary muscle thickness were obtained by Casia2, biomechanical parameters were obtained by Pentacam and Corvis ST

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
scleral and ciliary muscle thickness
Time Frame: one year
The thickness of scleral and ciliary muscle(Casia2, quantitative data through the utilization of its integrated ruler system)
one year
biomechanical parameters
Time Frame: one year
The biomechanical parameters(Corvis ST, exporting the quality-assured csv files to analysis)
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Tianjin Eye Hospital

Investigators

  • Study Chair: Yan Wang, Prof, TianJin eye hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 4, 2023

Primary Completion (Actual)

October 1, 2023

Study Completion (Actual)

October 1, 2023

Study Registration Dates

First Submitted

October 21, 2023

First Submitted That Met QC Criteria

October 28, 2023

First Posted (Actual)

October 31, 2023

Study Record Updates

Last Update Posted (Actual)

October 31, 2023

Last Update Submitted That Met QC Criteria

October 28, 2023

Last Verified

October 1, 2023

More Information

Terms related to this study

Other Study ID Numbers

  • KY2023025

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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