- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06559852
The Impact of Yoga on Endometriosis-Related Pain
May 20, 2026 updated by: Linda Li, Milton S. Hershey Medical Center
The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis.
Study Overview
Detailed Description
Yoga has been demonstrated to improve menstrual pain associated with primary dysmenorrhea through use of physical exercises, mental meditation, and breathing techniques.
Still, there has been limited studies assessing potential benefits of yoga on pain symptoms of endometriosis.
It is important to further assess yoga as a complementary therapy for women with endometriosis.
Study Type
Interventional
Enrollment (Estimated)
30
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Linda Li, MD
- Phone Number: 7175313503
- Email: lindali@pennstatehealth.psu.edu
Study Contact Backup
- Name: Ashlie Carter, MD
- Phone Number: 7175313503
- Email: acarter8@pennstatehealth.psu.edu
Study Locations
-
-
Pennsylvania
-
Hershey, Pennsylvania, United States, 17033
- Recruiting
- Penn State Health
-
Contact:
- Ashlie Carter, MD
- Phone Number: 7175313503
- Email: acarter8@pennstatehealth.psu.edu
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- Reproductive aged women 18-45
- Self-reported prior surgery with pathology confirming a diagnosis of endometriosis
- No current use of yoga
- Baseline moderate pain, score greater than or equal to 5 on VAS scoring
- Access to internet with wifi capability for zoom platform and completion of weekly surveys
- Access to items required for yoga session participation (2 blankets or towels, firm pillow, stable chair, wall space, comfortable clothing, water)
- Ability to commit to duration of 12-week yoga course
Exclusion Criteria:
- Pregnant patients
- Established yoga participation or moderate exercise regimen
- Physical trauma or disability
- Planned surgery or hormonal medication change during study
- Non-English speaking patients
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Yoga Intervention
|
Participants will engage in a 12-week virtual yoga course to assess impact on endometriosis-related pain
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Change in Endometriosis Health Profile-30 Pain Score
Time Frame: Baseline to completion at 12-weeks
|
Identify the impact of yoga on endometriosis related pain based on the Endometriosis Health Profile-30, with specific focus on the domain of pain.
The EHP-30 questionnaire consists of five scales which includes pain, control and powerlessness, emotional well-being, social support, and self-image and a total of 30 questions.
Each scale is translated into a score ranging from 0, or the best health status, to 100, the worst health status.
|
Baseline to completion at 12-weeks
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Change in Visual Analog Scale scores
Time Frame: Baseline to completion at 12-weeks
|
Comparison of visual analog scale scores from start to the end of the study.
The visual analog scale is a validated scale for measuring acute and chronic pain.
Scores are recorded on a scale between 0 or "no pain" and 10, the "worst pain".
|
Baseline to completion at 12-weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Estimated)
August 15, 2026
Primary Completion (Estimated)
September 15, 2026
Study Completion (Estimated)
September 15, 2026
Study Registration Dates
First Submitted
August 15, 2024
First Submitted That Met QC Criteria
August 15, 2024
First Posted (Actual)
August 19, 2024
Study Record Updates
Last Update Posted (Actual)
May 22, 2026
Last Update Submitted That Met QC Criteria
May 20, 2026
Last Verified
May 1, 2026
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Urogenital Diseases
- Genital Diseases
- Pain
- Neurologic Manifestations
- Female Urogenital Diseases
- Female Urogenital Diseases and Pregnancy Complications
- Genital Diseases, Female
- Pathological Conditions, Signs and Symptoms
- Signs and Symptoms
- Endometriosis
- Pelvic Pain
- Therapeutics
- Mind-Body Therapies
- Complementary Therapies
- Spiritual Therapies
- Exercise Movement Techniques
- Physical Therapy Modalities
- Yoga
Other Study ID Numbers
- STUDY00025723
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
IPD Plan Description
Plan to publish in an ICMJE journal upon completion of study.
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Endometriosis
-
Fabio BarraCompletedEndometriosis | Endometriosis, Rectum | Endometriosis of Vagina | Endometriosis Rectovaginal Septum | Endometriosis Pelvic | Endometriosis of ColonItaly
-
BioGene Pharmaceutical Ltd.WithdrawnSafety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis (ELTA)Endometriosis | Endometriosis Ovary | Endometriosis, Rectum | Endometriosis ExternaSwitzerland
-
Ospedale Policlinico San MartinoCompletedEndometriosis | Bowel Endometriosis | Endometriosis, Rectum | Endometriosis ColonItaly
-
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...CompletedEndometriosis | Endometriosis-related Pain | Endometriosis Thoracic | Endometriosis of Lung | Endometriosis of PleuraItaly
-
Ospedale Policlinico San MartinoCompletedEndometriosis, Rectum | Endometriosis, SigmoidItaly
-
Semmelweis UniversityUniversity of PecsNot yet recruitingEndometriosis | Endometriosis Ovary | Endometriosis Rectovaginal Septum
-
Catholic University of the Sacred HeartCompletedPelvic Endometriosis | Endometriosis Outside PelvisItaly
-
IRCCS Azienda Ospedaliero-Universitaria di BolognaUnknownBowel Endometriosis | Endometriosis, RectumItaly
-
Ospedale Policlinico San MartinoActive, not recruitingEndometriosis, Rectum | Endometriosis of ColonItaly
-
Catholic University of the Sacred HeartCompletedPelvic Endometriosis | Endometriosis Outside PelvisItaly
Clinical Trials on Yoga
-
Universität Duisburg-EssenCompleted
-
Ataturk UniversityKTO Karatay UniversityRecruiting
-
University of Texas at AustinCompleted
-
Adiyaman University Research HospitalCompletedDepression | Stress | Anxiety | Psychological ResilienceTurkey
-
NMP Medical Research InstituteYog-Kulam; Department of Zoology, University of Rajasthan, IndiaCompleted
-
NMP Medical Research InstituteWarwick Research Services; Yog-KulamCompleted
-
Northwestern UniversityCompleted
-
University of MinnesotaCompleted
-
Ohio State University Comprehensive Cancer CenterNational Cancer Institute (NCI)CompletedDepression | Pain | Breast Cancer | FatigueUnited States
-
Saglik Bilimleri UniversitesiThe Scientific and Technological Research Council of TurkeyCompletedStress | Anxiety | Telerehabilitation | Yoga | University StudentsTurkey