Influenza Reminder Text-Messaging

September 30, 2025 updated by: Children's Hospital of Philadelphia

Influenza Reminder Text-Messaging: A Randomized Quality Improvement Effort to Promote Influenza Vaccine in Pediatric Primary Care

Through a large, population-level quality improvement effort within the Children's Hospital of Philadelphia Care Network, we will evaluate text message reminders on flu vaccination rates for both patients with and without a scheduled well child care visit during flu season.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This is a randomized control trial with two patient cohorts: patients with and without a scheduled well child care visit during the upcoming 2024 flu season. Patients with a scheduled well child visit will be randomized into one of three groups (control, intervention message #1, or intervention message #2). Patients within the intervention groups will receive a one-time text message reminder to get their flu shot for their child at their child's upcoming well visit. Intervention groups will be texted at the same time, the same month as their child's well visit. The text message language will differ between groups. Patients without a scheduled upcoming well child visit during the 2024 flu season will also be randomized into one of three groups (control, intervention message #1, or intervention message #2). Intervention groups will be texted at the same time, at the start of flu season. The text message language will differ between groups.

Flu vaccine uptake will be measured within each patient cohort.

Study Type

Interventional

Enrollment (Actual)

228361

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Pennsylvania
      • Philadelphia, Pennsylvania, United States, 19146
        • The Children's Hospital of Philadelphia

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • All patients between ages 6 months-18 years old who have an upcoming well visit during the Fall of 2024 (September through December 2024) or had a completed well visit from January 2023 through August 2024
  • Patients have a mobile phone number within their medical record
  • Patients have opted-in to text communications from CHOP
  • English-speaking

Exclusion Criteria:

  • Subjects who do not meet the above inclusion criteria will be excluded

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Factorial Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
No Intervention: Cohort 1a
Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1a are those randomized to CONTROL and will not receive a text message reminder about getting their flu shot at their upcoming visit.
Experimental: Cohort 1b
Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1b are those randomized to INTERVENTION MESSAGE #1 and will receive text message reminder (variation #1) about getting their flu shot at their upcoming visit.
Behavioral: Text message reminder
One-time text message reminder with information about getting flu vaccine at CHOP
Experimental: Cohort 1c
Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1c are those randomized to INTERVENTION MESSAGE #2 and will receive text message reminder (variation #2) about getting their flu shot at their upcoming visit.
Behavioral: Text message reminder
One-time text message reminder with information about getting flu vaccine at CHOP
No Intervention: Cohort 2a
Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2a are those randomized to CONTROL and will not receive a text message reminder about getting their flu shot.
Experimental: Cohort 2b
Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2b are those randomized to INTERVENTION MESSAGE #1 and will receive text message reminder (variation #3) about getting their flu shot this upcoming flu season.
Behavioral: Text message reminder
One-time text message reminder with information about getting flu vaccine at CHOP
Experimental: Cohort 2c
Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2b are those randomized to INTERVENTION MESSAGE #2 and will receive text message reminder (variation #4) about getting their flu shot this upcoming flu season.
Behavioral: Text message reminder
One-time text message reminder with information about getting flu vaccine at CHOP

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The effectiveness of a text message reminder on influenza vaccine uptake
Time Frame: Baseline to approximately 30 days post-text message
Via prospective chart review, the primary outcome for both Cohort 1 and Cohort 2 will be to assess the number of patients who received an influenza vaccination 30 days post-text message reminder (baseline). Data from chart review will determine vaccination status (patient received influenza vaccination or not).
Baseline to approximately 30 days post-text message

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The effectiveness of text message language within Cohort 1
Time Frame: Baseline to approximately 30 days post-text message
Via prospective chart review, we will compare the number of patients within the Cohort 1 intervention groups who received influenza vaccination to understand which text message variation was more effective. Data from chart review will determine vaccination status (patient received influenza vaccination or not).
Baseline to approximately 30 days post-text message
The effectiveness of text message language within Cohort 2
Time Frame: Baseline to approximately 30 days post-text message
Via prospective chart review, we will compare the number of patients within the Cohort 2 intervention groups who received influenza vaccination to understand which text message variation was more effective. Data from chart review will determine vaccination status (patient received influenza vaccination or not).
Baseline to approximately 30 days post-text message

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Children's Hospital of Philadelphia

Investigators

  • Principal Investigator: Brian P. Jenssen, MD, Children's Hospital of Philadelphia

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 3, 2024

Primary Completion (Actual)

December 31, 2024

Study Completion (Actual)

December 31, 2024

Study Registration Dates

First Submitted

September 5, 2024

First Submitted That Met QC Criteria

September 5, 2024

First Posted (Actual)

September 19, 2024

Study Record Updates

Last Update Posted (Estimated)

October 1, 2025

Last Update Submitted That Met QC Criteria

September 30, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 24-022516

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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