Sleep and Resistance Exercise

May 23, 2025 updated by: Alberto Pérez-López, University of Alcala

Relationship Between Sleep Time and Quality With the Production of Force, Power, and Muscular Endurance.

Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood. Furthermore, the interaction between complete and partial sleep deprivation over one night and sleeping the usual hours for each person remains unclear.

Objectives: The aim of this study is to evaluate the effects of sleep deprivation on the production of strength, power, and muscular endurance according to sex (men vs. women) and type of exercise (bench press vs. squat). Additionally, the study will analyze the effects of sleep deprivation on perceived fatigue, mood, dietary habits, electrical activity, resting metabolic rate (RMR), and maximal fat oxidation (MFO).

Study Overview

Status

Completed

Conditions

Study Type

Interventional

Enrollment (Actual)

28

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Madrid
      • Alcalá de Henares, Madrid, Spain, 28805
        • Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Age between 18 and 35 years.
  • Body Mass Index (BMI) < 25 kg/m².
  • Resistance-trained individuals (more than 2 years of structured training).
  • Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
  • Participants must be able to perform the tests described in the following section.

Exclusion Criteria:

  • History of neuromuscular diseases, heart disease, or conditions that may affect liver or muscle metabolism.
  • Use of drugs, stimulants, or sports supplements that could interfere with the dietary supplement used in the study.
  • Sedentary habits (less than 150 minutes/week of moderate exercise).
  • Having undergone prolonged periods of physical inactivity in the 6 months prior to the study.
  • Engaging in strenuous exercise within 48 hours prior to the tests.
  • Failure to replicate the same food intake on both experimental days.
  • Consumption of caffeine or any other stimulant the day before the tests.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Placebo Comparator: 8h Sleep (at home)
Participants sleep 8h at home
8h sleep at home or in the laboratory
Experimental: 8h Sleep (Laboratory)
Participants sleep 8h in the lab
8h sleep at home or in the laboratory
Partial (4h) or total (0h) sleep deprivation
Experimental: 4h Sleep (Laboratory)
Participants sleep 4h in the laboratory
Partial (4h) or total (0h) sleep deprivation
Experimental: 0h Sleep (Laboratory)
Participants sleep 0h in the laboratory
Partial (4h) or total (0h) sleep deprivation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mean velocity at different %1RM
Time Frame: Through study completion, an average of 4 weeks
Measuring bar mean velocity desplacement during bench press and back squat exercises.
Through study completion, an average of 4 weeks
Peak velocity at different %1RM
Time Frame: Through study completion, an average of 4 weeks
Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.
Through study completion, an average of 4 weeks
Mean power output at different %1RM
Time Frame: Through study completion, an average of 4 weeks
Measuring during bench press and back squat exercises.
Through study completion, an average of 4 weeks
Peak power output and time to reach peak power output at different %1RM
Time Frame: Through study completion, an average of 4 weeks
Measuring during bench press and back squat exercises.
Through study completion, an average of 4 weeks
Bar velocity deplacement performed in 1 set at 65%1RM until task failure
Time Frame: Through study completion, an average of 4 weeks
In bench press and back squat exercises
Through study completion, an average of 4 weeks
Power output generated in 1 set at 65%1RM until task failure
Time Frame: Through study completion, an average of 4 weeks
In bench press and back squat exercise
Through study completion, an average of 4 weeks
Number of repetitions performed at 65%1RM until task failure
Time Frame: Through study completion, an average of 4 weeks
In bench press and back squat exercises
Through study completion, an average of 4 weeks
Resting Metabolic Rate (RMR)
Time Frame: Through study completion, an average of 4 weeks
Kcal at rest measuring a metabolic chart
Through study completion, an average of 4 weeks
Maximal Fat Oxidation Rate
Time Frame: Through study completion, an average of 4 weeks
g/min using a metabolic chart
Through study completion, an average of 4 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fat mass
Time Frame: Through study completion, an average of 4 weeks
Using electrical bioimpedance (kg and % of body mass)
Through study completion, an average of 4 weeks
Fat-free mass
Time Frame: Through study completion, an average of 4 weeks
Using electrical bioimpedance (kg and % of body mass)
Through study completion, an average of 4 weeks
Physical activity (METs-min/wk)
Time Frame: Before each trial, during the 4 weeks
Using IPAQ
Before each trial, during the 4 weeks
Dietary habits (g/kg of macronutrients)
Time Frame: Before each trial, during the 4 weeks
Using a 24-total recall
Before each trial, during the 4 weeks
Mood state (tension, depression, anger, vigor, fatigue and confusion)
Time Frame: Through study completion, an average of 4 weeks
Participants graded a set of 29 items related to the mood on a Likert scale from 0 (not at all) to 4 (extremely) in reply to the question;How do you feel at this moment?; to assess six scales: tension, depression, anger, vigor, fatigue and confusion.
Through study completion, an average of 4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 7, 2024

Primary Completion (Actual)

January 30, 2025

Study Completion (Actual)

January 30, 2025

Study Registration Dates

First Submitted

September 9, 2024

First Submitted That Met QC Criteria

September 18, 2024

First Posted (Actual)

September 23, 2024

Study Record Updates

Last Update Posted (Actual)

May 25, 2025

Last Update Submitted That Met QC Criteria

May 23, 2025

Last Verified

May 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • CEID/2023/6/119

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Sleep Deprivation

Clinical Trials on Sleep place

Subscribe