Sensory Interaction and Balance Control During Standing and Walking in Healthy Young and Older Adults

October 4, 2024 updated by: Pieter Meyns, Hasselt University

Sensory Interaction and Balance Control During Standing and Walking Under Challenging Conditions in Healthy Young and Older Adults

This project is designed to: a) develop a new test called UHasselt Locomotor Sensory Integration Test (UHLSINT) which would allow us to evaluate sensory interaction process in locomotion assess whether Locomotor CTSIB and to investigate whether UHLSINT is a reliable test to evaluate sensory interaction in both young and older adults, b) evaluate the difference in sensory interaction and balance performance between standing and walking between both young and older adults, c) examine the changes in sensory interaction process under challenging conditions such as perturbations, dual-task, and when both are present between both young and older adults, d) examine the association between overall fall risk defined by the single-large perturbations and sensory interaction processes used during all the trials in both age groups.

In order to achieve these aims, 10 trials will be conducted:

Trial 1- Single-Large Perturbation in Standing Trial 2- Single-Large Perturbation in Walking Trial 3- Instrumented CTSIB Trial 4- Locomotor CTSIB Trial 5- Instrumented CTSIB + Perturbations Trial 6- Locomotor CTSIB + Perturbations Trial 7- Instrumented CTSIB + Auditory Stroop Test Trial 8- Locomotor CTSIB + Auditory Stroop Test Trial 9- Instrumented CTSIB + Perturbations + Auditory Stroop Test Trial 10- Locomotor CTSIB + Perturbations + Auditory Stroop Test

Two different treadmill perturbations will be applied in addition to the Instrumented CTSIB and UHLSINT: a) slip perturbations, b) continuous perturbations. An auditory stroop task will be applied in relevant trials.

All of the trials will be performed in CAREN High-End Systems (Motek Medical BV, Amsterdam, The Netherlands) which is a motion capture system that is equipped with a treadmill mounted on a 6 degree of freedom motion base, a 360º dome-shaped virtual reality (VR) screen, and a marker-based movement analysis system.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

64

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Belgium
      • Diepenbeek, Belgium, 3590
        • Hasselt University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

Healthy young and older adults

Description

Inclusion Criteria:

  • Young adults who: a) aged between 18 to 35 years old and, b) have never been diagnosed with somatosensory, visual, and vestibular deficits as reported by the participants, will be invited to participate. Community-dwelling older adults who: a) are 65 years old and over and, b) have not fallen in the last 12 months will also be invited to participate.

Exclusion Criteria:

  • having had serious lower extremity injuries or operations in the past year,
  • having any neurological (stroke, epilepsy, Parkinson's disease, etc.), sensory (i.e. peripheral neuropathy, diminished sense of pain, etc.) or motor disorder that can interfere with the results of the study
  • Diagnosed vascular, respiratory, cardiac, orthopedic, or other disorders that affect the subject's ability to exercise safely,
  • Medication affecting exercise tolerance. Additionally, based on the CAREN High-End Systems contraindications and risk factors the following exclusion criteria will be applied to the participants: a) a body weight higher than the 135 kg, b) an inability to properly adjust the harness to the respective body part due to pregnancy, colostomy bags, skin lesions that cannot be protected appropriately and any other reason that prevents a proper, pain-free adjustment of the harness.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Young Adults
a) aged between 18 to 35 years old and, b) have never been diagnosed with somatosensory, visual, and vestibular deficits as reported by the participants
Other: No intervention
This is a observational study and the participants will not receive any intervention
Older Adults
a) are 65 years old and over and, b) have not fallen in the last 12 months will also be invited to participate
Other: No intervention
This is a observational study and the participants will not receive any intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Instrumented CTSIB
Time Frame: Baseline

The Clinical Test of Sensory Integration and Balance (CTSIB) is a tool used to evaluate a person's sensory integration process by manipulating different sensory inputs. It assesses how well the body uses three main sensory systems-visual, vestibular, and proprioceptive inputs-to maintain postural control. Six conditions are included in the test, each progressively altering the availability of sensory information:

Condition 1: Eyes Open, Firm Surface Condition 2: Eyes Closed, Firm Surface Condition 3: Eyes Open, Foam Surface Condition 4: Eyes Closed, Foam Surface Condition 5: Visual Conflict, Firm Surface Condition 6: Visual Conflict, Foam Surface
Baseline
UHasselt Locomotor Sensory Integration Test
Time Frame: Baseline
This test was developed to evaluate sensory integration in locomotion.
Baseline

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Center of Mass
Time Frame: Baseline
Center of mass displacement changes between the trials will be compared to achieve the aims of the study.
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hasselt University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

October 7, 2024

Primary Completion (Estimated)

October 15, 2026

Study Completion (Estimated)

December 25, 2026

Study Registration Dates

First Submitted

October 3, 2024

First Submitted That Met QC Criteria

October 4, 2024

First Posted (Actual)

October 8, 2024

Study Record Updates

Last Update Posted (Actual)

October 8, 2024

Last Update Submitted That Met QC Criteria

October 4, 2024

Last Verified

September 1, 2024

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • HasseltU100

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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