Clinical Evaluation of the Effectiveness of the Er:Cr:YSGG Laser in Reducing Dentin Sensitivity

October 27, 2024 updated by: Can Tho University of Medicine and Pharmacy

Clinical Evaluation of the Effectiveness of the Er:Cr:YSGG Laser in Reducing Dentin Sensitivity: A Cross-Sectional Study

This study aims to evaluate the clinical effectiveness of the Er:Cr laser in reducing dentin hypersensitivity (DH), a common dental condition characterized by sharp pain in response to thermal, mechanical, chemical, or osmotic stimuli.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Dentin Hypersensitivity is one of the common and uncomfortable clinical issues for patients, characterized by sharp pain when the dentinal tubules are stimulated by thermal, mechanical, chemical, or osmotic agents. This sensitivity often appears in the canine and premolar areas, particularly in the cervical third of the tooth surface. The main cause of DH is dentin exposure, which occurs when the enamel or cementum covering the root surface is lost, usually due to factors such as improper brushing techniques, erosion-induced abrasion, or harmful habits like bruxism. Dentin exposure can also occur due to periodontal disease, gingival recession, or periodontal interventions, such as root planing. One of the most widely accepted theories explaining the mechanism of DH is the hydrodynamic theory proposed by Brännström in 1984. According to this theory, when the dentinal tubules are exposed, pressure changes in the surrounding tissue cause fluid movement within the tubules, stimulating mechanoreceptors in the pulpal nerves, resulting in sharp pain. The diagnosis and treatment of DH are complex due to its multifactorial nature, requiring thorough examination to rule out other oral pathologies and ensure the health of the pulp and gingiva.

Various treatment methods for DH have been proposed in the literature, ranging from modifying brushing habits, guiding patients on diet, occlusal adjustment, to using desensitizing agents such as potassium nitrate, potassium oxalate, and calcium phosphate. Some approaches also involve using bonding systems, adhesive materials, or even lasers to occlude the dentinal tubules and reduce sensitivity. In recent years, the use of dental lasers as an alternative treatment for DH has gained significant attention from researchers. Commonly used lasers include high-power lasers such as Nd:YAG, Er:YAG, Er,Cr:YSGG… as well as low-power lasers in photobiomodulation therapy. The Er,Cr:YSGG laser is of particular interest due to their operation at a wavelength of 2780 nm, which is highly absorbed by water. This allows for the evaporation of fluid in the dentinal tubules, leaving insoluble salts that help seal the tubules and reduce sensitivity symptoms. According to a study by Yilmaz et al. (2011), the Er,Cr:YSGG laser not only provides rapid relief but also maintains its effect for up to three months without causing significant side effects.

Due to the subjective nature of DH, assessing the level of sensitivity is often challenging. However, measurement tools such as the Visual Analog Scale VAS or Yeaple pressure probe have been used in studies to provide more reliable measurement results. The objective of this study is to evaluate the effectiveness of the Er,Cr:YSGG laser in the treatment of DH.

Study Type

Interventional

Enrollment (Actual)

36

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Vietnam
      • Cần Thơ, Vietnam, 900000
        • Can Tho University of Medicine and Pharmacy

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Patients >18 years old
  • Express a desire for treatment for their dentin hypersensitivity
  • Only sensitive teeth without indications for restorative procedures were considered eligible
  • Informed consent was obtained from all participants

Exclusion Criteria:

- Patients with underlying systemic conditions or those taking medications that could affect the study outcomes, such as analgesics, anti-inflammatory drugs, or sedatives within 72 hours prior to enrollment

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Dentin sensitivity was measured before and after treatment
Dentin sensitivity was measured using the Yeaple Probe and air stimulation tests before and after treatment
Diagnostic test: Dentin sensitivity was measured using the Yeaple Probe and air stimulation tests before and after treatment
Dentin sensitivity was measured using the Yeaple Probe and air stimulation tests before and after treatment. The effectiveness of the treatment was assessed at baseline, 30 minutes, 1 week, and 1 month post-treatment using the Visual Analog Scale (VAS) and Yeaple Probe scores.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The objective of this study is to evaluate the effectiveness of the Er,Cr:YSGG laser in the treatment of Dentin Sensitivity
Time Frame: Dentin sensitivity was measured using the Yeaple Probe and air stimulation tests before of the Er,Cr:YSGG laser in the and after treatment.
The objective of this study is to evaluate the effectiveness of Dentin Sensitivity using the Yeaple Probe
Dentin sensitivity was measured using the Yeaple Probe and air stimulation tests before of the Er,Cr:YSGG laser in the and after treatment.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Can Tho University of Medicine and Pharmacy

Investigators

  • Principal Investigator: Quang Xuan Vo, Can Tho University of Medicine and Pharmacy

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 15, 2023

Primary Completion (Actual)

June 1, 2024

Study Completion (Actual)

June 15, 2024

Study Registration Dates

First Submitted

October 19, 2024

First Submitted That Met QC Criteria

October 19, 2024

First Posted (Actual)

October 22, 2024

Study Record Updates

Last Update Posted (Actual)

October 30, 2024

Last Update Submitted That Met QC Criteria

October 27, 2024

Last Verified

June 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Vo Xuan Quang

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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