INVESTIGATION OF THE INTRAOPERATIVE AND POSTOPERATIVE EFFECTS OF EXTERNAL OBLIQUE INTERCOSTAL PLAN BLOCK IN PATIENTS UNDERGOING LAPARASCOPIC CHOLESYSTECTOMY OPERATION

INVESTIGATION OF THE INTRAOPERATIVE AND POSTOPERATIVE EFFECTS

Objective: Regional anesthesia techniques, such as peripheral nerve blocks, have a lower side effect profile and higher patient satisfaction compared to central blocks. With the introduction of Ultrasonography (USG), these techniques have become more commonly and reliably performed. The purpose of our study is to compare parameters such as intraoperative hemodynamics, postoperative analgesic requirement, and patient satisfaction between patients undergoing External Oblique Intercostal Plane Block (EOIB) with those who did not receive EOIB, which has few studies conducted on it.

Study Overview

• Status: Completed
• Conditions: Laparoscopic Cholecystectomy
• Intervention / Treatment: Procedure: External Oblique Intercostal Plane Block; Drug: control group

• Study Type: Observational
• Enrollment (Actual): 64
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Kayapınar
    • Diyarbakır, Kayapınar, Turkey (Türkiye), 21070
      • Health Sciences University Gazi Yaşargil Training and Research Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

operating

Description

Inclusion Criteria:

• Patients aged between 18-65
• and with ASA1-2 were included.

Exclusion Criteria:• Patients younger than 18 years of age and older than 65 years of age

• Patients allergic to local anesthetics
• Patients with opioid and alcohol addiction
• Patients with perioperative signs of acute cholecystitis
• Patients with contraindications for laparoscopic surgery
• Cases with ASA III-IV were not included in the study.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
External oblique intercostal plan block group; After endotracheal intubation, a 22-gauge 100 mm long block needle will be inserted at the T6-T7 level under USG guidance and bilateral EOIB will be applied with 20 cc of 0.25% Bupivacaine on each side under the external oblique intercostal muscle (total 40ml bilaterally).	Procedure: External Oblique Intercostal Plane Block; After endotracheal intubation, a 22-gauge 100 mm long block needle will be inserted at the T6-T7 level under USG guidance and bilateral EOIB will be applied with 20 cc of 0.25% Bupivacaine on each side under the external oblique intercostal muscle (total 40ml bilaterally).
control group; No Intervention	Drug: control group; No intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Numeric Rating Scale	They will be numbered from 1 to 10. If reporting a score on a scale, please include the unabbreviated scale title, the minimum and maximum values, and whether higher scores mean a better or worse outcome	Postoperative 30.second,2 hours, 6 hours,12 hours,24 hours
Visual Analogue Scale	The Visual Analogue Scale (VAS) is a subjective measure of pain. It consists of a 10cm line with two endpoints representing 'no pain' and 'worst pain imaginable'. Patients are asked to rate their pain by placing a mark on the line corresponding to their current level of pain. The distance along the line from the 'no pain' marker is then measured with a ruler giving a pain score out of 10.	Postoperative 30.second,2 hours, 6 hours,12 hours,24 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Riker Sedation Agitation Scale	7 Dangerous Agitation ... If reporting a score on a scale, please include the unabbreviated scale title, the minimum and maximum values, and whether higher scores mean a better or worse outcome.	Immediately after extubation
Patient satisfaction score	Patients' satisfaction with the quality of pain management will be evaluated on the second postoperative day using the following scale: 1 = very unsatisfied; 2 = highly dissatisfied; 3 = medium; 4 = very satisfactory; 5 = very satisfactory	at the 24th postoperative hour
Postoperative vomiting and nausea	Postoperative vomiting and nausea: yes or no	Postoperative 30.second,2 hours, 6 hours,12 hours,24 hours
Opioid use	Tramadol use	Postoperative 24 hours
Mean Arter Pressure	mm/hg	when you come to the operating room table, after block Intraoperative 10 minutes,30 minutes postoperative 2,6,12 hours
Heart Rate	beats/minute	when you come to the operating room table, after block Intraoperative 10 minutes,30 minutes postoperative 2,6,12 hours

Collaborators and Investigators

• Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Study record dates

Study Major Dates

• Study Start (Actual): November 26, 2024
• Primary Completion (Actual): December 26, 2024
• Study Completion (Actual): December 30, 2024

Study Registration Dates

• First Submitted: November 26, 2024
• First Submitted That Met QC Criteria: November 26, 2024
• First Posted (Actual): December 2, 2024

Study Record Updates

• Last Update Posted (Actual): November 24, 2025
• Last Update Submitted That Met QC Criteria: November 18, 2025
• Last Verified: November 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Investigative Techniques; Epidemiologic Research Design; Epidemiologic Methods; Research Design; Methods; Control Groups
• Other Study ID Numbers: mazlum

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No