Serious Game to Teach Opioid Overdose Response

Using a Serious Game to Teach People How to Recognize and Respond to Opioid Overdose

This study evaluates the efficacy of a serious game to teach students how to recognize and respond to opioid overdose

Study Overview

• Status: Not yet recruiting
• Conditions: Opioid Overdose
• Intervention / Treatment: Other: Serious game training

Detailed Description

This study uses an interactive realistic film depicting an opioid overdose to teach high school/middle school students how to recognize and respond to opioid overdose. The film features a person who finds their friend unresponsive, with evidence of opioid use. The unresponsive friend demonstrates signs of opioid overdose. The hero must recognize opioid overdose, administer naloxone (opioid antedote) and perform CPR. The film is made interactive by the narrator pausing the action of the film, and asking learners to answer questions/make choices.

Efficacy is tested on the day of training, and 2-4 months later. Efficacy is measured by student ability to correctly administer naloxone to a manikin, perform CPR, and answer knowledge questions about opioid overdose. Other studied metrics include student engagement/enjoyment, attitudes/biases, and emotions created by the training. These will be tested through validated questionnaires.

• Study Type: Interventional
• Enrollment (Estimated): 850
• Phase: Phase 2

Contacts and Locations

• Study Contact: Name: Associate Professor, MD; Phone Number: 7756828239; Email: ltoft@unr.edu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Student at participating school, enrolled in Health or Science Class

Exclusion Criteria:

• None

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Control; No intervention/training
Experimental: Serious Game; Serious Game training to respond to opioid overdose	Other: Serious game training; A serious game featuring a dramatic/realistic film, pauses with questions for active learning, and practice administration of naloxone and performing CPR

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Naloxone administration Skill	Properly administer naloxone to a victim of opioid overdose Study personnel will ask students to administer naloxone to a CPR manikin. Personnel will use a checklist from the Center for Addiction and Mental Health to score student responses.	Day of training, and 2-3 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
CPR Skill	Ability to perform high-quality CPR Students will be asked to perform CPR on a CPR manikin for 2 minutes. CPR skill will be measured with the CPR Meter 2 from Laerdal, which reports compression rate, depth, and percent recoil. We will consider "high quality CPR" students who perform 70% or more of compressions at appropriate rate (100-120/min), depth (2-2.5inches), and full recoil.	Day of training, and 2-3 months
Attitudes towards opioid overdose	Attitudes, enjoyment, and emotions towards opioid overdose Emotions will be measured using the PANAS scale (Positive And Negative Affect Scale) which consists of 10 positive and 10 negative emotion words. The total score is calculated by finding the sum of the 10 positive items, and then the 10 negative items. Scores range from 10 - 50 for both sets of items. For the total positive score, a higher score indicates more of a positive affect. Engagement and enjoyment will be measured using Likert-style questions asking for agreement with statements such as "I enjoyed CPR training," "CPR training was fun," "I will use CPR training in the future," "It is important to learn CPR" Attitudes will be measured with a custom questionnaire asking Likert-style responses to statements regarding opioid overdose.	Day of training, and 2-3 months
Knowledge of opioid overdose response	Knowledge of how to recognize and respond to opioid overdose A questionnaire of custom-created multiple choice questions will assess student knowledge of how to recognize and respond to opioid overdose.	Day of training, and 2-3 months

Collaborators and Investigators

• Sponsor: University of Nevada, Reno

Study record dates

Study Major Dates

• Study Start (Estimated): February 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2027

Study Registration Dates

• First Submitted: December 3, 2024
• First Submitted That Met QC Criteria: December 5, 2024
• First Posted (Estimated): December 11, 2024

Study Record Updates

• Last Update Posted (Estimated): December 11, 2024
• Last Update Submitted That Met QC Criteria: December 5, 2024
• Last Verified: December 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Narcotic-Related Disorders; Drug Misuse; Mental Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Prescription Drug Misuse; Opioid-Related Disorders; Opiate Overdose; Drug Overdose
• Other Study ID Numbers: 2159620

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: Participants are minors and therefore protected. No IDP will be shared

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No