Effect of Mulligan Medial/Lateral Glide w/wo Compression/Decompression Technique on Pain ROM and Function KO

Effect of Mulligan Medial/Lateral Glide With and Without Compression/ Decompression Technique on Pain, Range of Motion and Function on Patients With Knee Osteoarthritis

The Effect of Mulligan Medial/Lateral Glide Techniques with and without Compression-Decompression on Pain, Range of Motion and Function in Patients with Knee Osteoarthritis. This study aims to investigate these effects to develop more effective, non-invasive treatment protocols for improving pain, range of motion and overall function in knee OA

Study Overview

• Status: Active, not recruiting
• Conditions: Knee Osteoarthritis
• Intervention / Treatment: Combination product: Mulligan Medial/Lateral glide with compression/ decompression technique; Combination product: Mulligan Medial/Lateral glide

Detailed Description

patients, for the better understanding of response by both treatments (i.e Mulligan medial/lateral glide with and without compression/decompression technique). Patient which meet inclusion criteria, gave their consent.

• Study Type: Interventional
• Enrollment (Actual): 54
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Lahore, Punjab, Pakistan
      • Services Hospital, Shadman 1

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria

• Unilateral Knee OA, Males and females between 30 and 60 years of age,
• Patients with restricted ROM,
• Patients are having more than grade III strength of knee muscles,
• l Willingness to take part in the intervention and evaluations

Exclusion Criteria:

• Patients having unstable knee joint after Total Knee Arthroplasty or medical conditions affecting rehabilitation,
• l Joint infection of hip and knee,
• l Soft tissue injuries around knee joints,
• including tendinitis and bursitis,
• l Any fracture including patellar fracture, femur or tibia

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Interventional group I	Combination product: Mulligan Medial/Lateral glide with compression/ decompression technique; Warm up (10 minutes with hot pack) and cool down exercises for a period of 5 to 10 minutes was given before starting and after the completion of exercises in supervised exercise program in all the groups. The following ergonomical advice were given to all the subjects, Avoid extreme knee bent positions, avoid squatting, crossed-leg sitting, frequent stair climbing or lifting heavy objects, avoid fatiguing postures except for infrequent short durations tasks, change posture frequently and use support where possible and avoid giving excess strain to the knees. Mulligan mobilisation consisted of Medial glide mobilisation with movement, Lateral glide mobilisation with movement, with active knee flexion (61) depending on the subjects condition. The gliding force was sustained while the patient performed 3 sets of 10 repetitions. Total 12 treatment sessions was given to each subject with the frequency of 3 sessions per week for 4 consecutive weeks.
Active Comparator: Interventional group II	Combination product: Mulligan Medial/Lateral glide; Warm up (10 minutes with hot pack) and cool down exercises for a period of 5 to 10 minutes was given before starting and after the completion of exercises in supervised exercise program in all the groups. The following ergonomical advice were given to all the subjects, Avoid extreme knee bent positions, avoid squatting, crossed-leg sitting, frequent stair climbing or lifting heavy objects, avoid fatiguing postures except for infrequent short durations tasks, change posture frequently and use support where possible and avoid giving excess strain to the knees. Total 12 treatment sessions was given to each subject with the frequency of 3 sessions per week for 4 consecutive weeks. After completing the therapeutic session, post- intervention data of the outcome parameters were taken.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Pain Rating Scale (NPRS)	This tool was utilized to assess the intensity of pain. A score of 0 denotes ""having no pain at all,"" while a score of 10 indicates ""the worst pain I've ever experienced."" The participants were asked to choose a number on the scale that accurately represented how much knee discomfort they were experiencing.According to a study conducted on individuals with knee OA, the interclass correlation was 0.95. Higher scores denote more intense pain; scores range from 0 to 10.	12 Months
Western Ontario and McMaster Osteoarthritis Index (WOMAC)	It is commonly used to assess lower extremity functional status, discomfort, and associated stiffness. The questionnaire consists of twenty-four questions: seventeen pertain to physical status, five concern pain status, and two address stiffness. Each question contains five alternatives starting from 0 which signifies no symptom or trouble at all to 4 which represents considerable difficulty in doing activities with severe symptoms. There are subscale scores for stiffness, discomfort, and functional status. The sum of the 24 items that were listed, with scores ranging from 0 to 96, was the definition of the total scores.	12 months

Collaborators and Investigators

• Sponsor: Superior University

Study record dates

Study Major Dates

• Study Start (Actual): February 15, 2024
• Primary Completion (Actual): August 1, 2024
• Study Completion (Estimated): March 1, 2025

Study Registration Dates

• First Submitted: December 26, 2024
• First Submitted That Met QC Criteria: December 26, 2024
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: December 26, 2024
• Last Verified: December 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Arthritis; Joint Diseases; Rheumatic Diseases; Osteoarthritis; Osteoarthritis, Knee
• Other Study ID Numbers: MSRSW/Batch-Fall22/761

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No