Vibraimage Technology for Detecting Depression in Psychiatric Outpatients

Diagnostic Accuracy of Vibraimage Technology for Detecting Depression in a Psychiatric Outpatient Setting

Vibraimage technology captures high-frame-rate images of head-neck movements, converting them into vibraimages that display muscle vibration amplitude and frequency. Using algorithms and calculations, it derives an emotional index from these images. This non-contact, objective method analyzes psychological indicators through micro-movement detection. An algorithm has been developed to detect depression by calculating 12 emotional and 2 psychophysiological parameters. This diagnostic accuracy study aims to validate the technology's ability to diagnose depression in psychiatric outpatients.

Study Overview

• Status: Completed
• Conditions: Depression
• Intervention / Treatment: Diagnostic test: Video capture

• Study Type: Observational
• Enrollment (Actual): 601

Contacts and Locations

Study Locations

• China
  • Beijing, China, 100096
    • Beijing HuiLongGuan Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Psychiatric outpatients attending the Beijing Huilongguan Hospital during the study period.

Description

Inclusion Criteria:

• Aged 18 to 70 years.
• No difficulties in reading or writing Chinese; fluent in Mandarin.
• Currently not taking psychotropic medications or on a stable dose for at least 6 weeks.
• Provided informed consent to participate in the study.

Exclusion Criteria:

• Schizophrenia.
• Bipolar disorder.
• History of organic brain disease or significant head trauma.
• Presence of severe systemic medical conditions.
• Suicidal ideation or a score ≥3 on Item 3 ("Suicide") of the 17-item Hamilton Depression Rating Scale (HAMD-17).
• Substance dependence or abuse.
• Intellectual disability or dementia.
• Inability to complete video capture or cooperate due to uncontrollable factors (e.g., hyperactivity, Parkinson's disease, or other conditions that prevent remaining still)

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Depressed Group; This group consists of individuals who were ultimately diagnosed with depression by a specialist physician.	Diagnostic test: Video capture; A 20-second video capture of head-neck movements at high frame rates is conducted for all participants to obtain high-resolution images. The captured videos are analyzed using an algorithm based on Vibraimage technology to infer whether the participants have depression.
Non-Depressed Group; This group consists of individuals who were ultimately diagnosed as not having depression by a specialist physician.	Diagnostic test: Video capture; A 20-second video capture of head-neck movements at high frame rates is conducted for all participants to obtain high-resolution images. The captured videos are analyzed using an algorithm based on Vibraimage technology to infer whether the participants have depression.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
discrimination	The primary outcome measure is the diagnostic discrimination of Vibraimage technology for depression, assessed by calculating the area under the receiver operating characteristic (ROC) curve. Participants first undergo video capture, followed by a clinical diagnosis of depression by a physician. Both the physician and participants are blinded to the results of the video analysis.	Participants undergo video capture and same-day clinical diagnosis by a physician. Video analysis and suggestive diagnosis are completed on the following day.

Collaborators and Investigators

• Sponsor: Peking University People's Hospital
• Collaborators: Beijing HuiLongGuan Hospital

Study record dates

Study Major Dates

• Study Start (Actual): January 26, 2025
• Primary Completion (Actual): March 1, 2025
• Study Completion (Actual): March 1, 2025

Study Registration Dates

• First Submitted: January 20, 2025
• First Submitted That Met QC Criteria: January 20, 2025
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: March 1, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Behavioral Symptoms; Mood Disorders; Depression; Depressive Disorder
• Other Study ID Numbers: Vibraimage_Psychiatric

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: De-identified individual participant data will be made available to qualified researchers upon reasonable request. Data sharing will be subject to approval by the principal investigator (PI) and the study sponsor.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No